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FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology

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Online First Differential chemoproteomic analysis of RRS-1 candidate molecule and molecules of several nonsteroidal anti-inflammatory drugs Abstract  similar documents
P. A. Galenko-Yaroshevsky, I. Yu. Torshin, A. N. Gromov, O. A. Gromova, K. F. Suzdalev, R. A. Murashko, A. V. Zelenskaya, A. V. Zadorozhniy, T. R. Glechyan, G. V. Simavonyan, E. M.I. Muhammad
"... of candidate molecule RRS-1 (N-{(Z)-2-(1-methyl-1H-indol-3-yl)-1-[(propylamino)carbonyl]vinyl}benzamide) from ..."
 
Vol 17, No 3 (2024) Differential chemoproteomic analysis of RRS-1 candidate molecule and molecules of several nonsteroidal anti-inflammatory drugs Abstract  similar documents
P. A. Galenko-Yaroshevsky, I. Yu. Torshin, A. N. Gromov, O. A. Gromova, K. F. Suzdalev, R. A. Murashko, A. V. Zelenskaya, A. V. Zadorozhniy, T. R. Glechyan, G. V. Simavonyan, E.M. I. Muhammad
"... of candidate molecule RRS-1 (N-{(Z)-2-(1-methyl-1H-indol-3-yl)1-[(propylamino)carbonyl]vinyl}benzamide) from ..."
 
Vol 17, No 2 (2024) Lignan 7-hydroxymatairesinol in the context of post-genomic pharmacology Abstract  similar documents
А. N. Rubashkina, I. Yu. Torshin, O. A. Gromova, A. N. Galustyan
"... it possible to assess the effect of drugs on genome transcription (transcriptome) and on the proteome ..."
 
Vol 17, No 3 (2024) Chemoproteomic analysis of the pharmacological properties of vitamin В12 derivatives Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, I. A. Dereven’kov, L. A. Maiorova
"... of heptaethanolamine, heptaethylenediamine, heptamethyl and heptabutyl cobyrinates) with human proteome proteins ..."
 
Vol 17, No 4 (2024) Chemoreactome prediction of anti-inflammatory, analgesic, ulcerogenic effects of the candidate molecule N-allylimidazole-zinc in comparison with zinc derivatives of nonsteroidal anti-inflammatory drugs Abstract  similar documents
P. A. Galenko-Yaroshevsky, A. V. Sergeeva, I. Yu. Torshin, A. N. Gromov, I. A. Reyer, O. A. Gromova, B. A. Trofimov, L. N. Parshina, R. A. Murashko, A. V. Zadorozhniy, A. V. Zelenskaya, N. S. Sergeev, Yu. V. Tovkach, O. N. Gulevskaya, I. V. Sholl
"... with the inhibition of kinin receptors, weak antihistaminic and antinociceptive properties. The molecule may exhibit ..."
 
Vol 18, No 1 (2025) Systematic analysis of molecules regulating nitric oxide (NO) metabolism and vascular endothelium condition Abstract  similar documents
I. Yu. Torshin, A. G. Chuchalin, O. A. Gromova
"... Background. Nitric monooxide (NO) is a signaling molecule that plays an important role in many ..."
 
Vol 15, No 1 (2022) Efficacy of targeted drugs for the treatment of adults with moderate-to-severe plaque psoriasis in the Russian Federation: a systematic literature review update Abstract  similar documents
V. D. Sokolova, N. A. Sableva, V. V. Mladov, D. G. Tolkacheva
"... (TNFα) inhibitors (INF, ADA, ETN), small molecules (TOFA and APR), and IL-12/23 inhibitor UST, while NTK ..."
 
Vol 14, No 4 (2021) Prospects of using chondroprotectors for the treatment of pulmonary pathology Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, A. G. Chuchalin
"... -receptors, increased levels of cytokines, degranulation of mast cells, etc.) by CS and GS provide ..."
 
Vol 15, No 2 (2022) Biophysical modeling indicates a high affinity of ethyl esters of omega-3 polyunsaturated fatty acids to the enzymes of the pro-inflammatory arachidonic acid cascade Abstract  similar documents
I. Yu. Torshin, O. A. Gromova
"... at various initial positions of the molecule relative to the receptor pocket and the molecular energy ..."
 
Vol 17, No 4 (2024) Proteomic analysis of synergetic neuroprotective effect of adenosine, thiamine, niacin and cyanocobalamin in pathophysiology of diabetic polyneuropathy Abstract  similar documents
O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok
"... and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular ..."
 
Vol 17, No 2 (2024) Chemoreactomic study of fonturacetam effects: molecular mechanisms of influence on adipose tissue metabolism Abstract  similar documents
O. A. Gromova, I. Yu. Torshin
"... and methods. Chemoreactomic, pharmacoinformatic and chemoneurocytological methods of molecule properties ..."
 
Vol 16, No 1 (2023) Modern biomarkers of acute kidney injury Abstract  similar documents
D. I. Korabelnikov, M. O. Magomedaliev
"... -microglobulin, kidney injury molecule-1, fatty acid binding protein) over the conventional glomerular filtration ..."
 
Vol 18, No 2 (2025) Chemoreactomic analysis of the drug prototype pilim-1 in comparison with zinc derivatives of nonsteroidal anti-inflammatory drugs Abstract  similar documents
P. A. Galenko-Yaroshevsky, I. Y. Torshin, A. N. Gromov, I. A. Reyer, O. A. Gromova, B. A. Trofimov, L. N. Parshina, R. A. Murashko, O. V. Shelemekh, A. V. Zadorozhniy, V. L. Popkov, A. V. Zelenskaya, I. B. Nektarevskaya, A. V. Sergeeva, A. V. Uvarov, Yu. V. Tovkach, I. V. Sholl
"... the need to explore new molecule candidates with reduced ulcerogenic effects. The zinc-containing molecule ..."
 
Vol 17, No 1 (2024) Chemoreactomic analysis of acyzole in comparison with zinc derivatives of nonsteroidal anti-inflammatory drugs Abstract  similar documents
P. A. Galenko-Yaroshevsky, I. Yu. Torshin, A. N. Gromov, O. A. Gromova, R. A. Murashko, A. V. Zelenskaya, L. O. Alukhanyan, O. V. Shelemekh
"... molecules with the structures of millions of other molecules with established molecular pharmacological ..."
 
Vol 16, No 4 (2023) Comparative chemomicrobiomic analysis of bacteriocins Abstract  similar documents
I. Yu. Torshin, O. A. Gromova
"... bacteria). Results. Compared to other molecules, bacteriocin C was characterized by lower MIC constants ..."
 
Vol 18, No 1 (2025) Chemoinformatic study of spiramycin in comparison with other antibiotics Abstract  similar documents
O. A. Gromovа, I. Yu. Torshin
"... the spiramycin molecule and the comparison molecules in terms of efficacy, safety and mechanisms of action ..."
 
Vol 17, No 3 (2024) Chemoreactomic analysis of the antioxidant properties of vitamin B12 derivatives Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, L. A. Maiorova
"... and pharmacological properties. The development of methods for predicting the properties of these molecules based ..."
 
Vol 16, No 3 (2023) The prospects for the use of vitamin B12 derivatives in pharmacology Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, L. A. Maiorova
"... , and the effects of interactions of these modified corrins with “small” inorganic and organic molecules ..."
 
Vol 17, No 1 (2024) Chemoreactome screening of aquacobalamin and heptamethyl ester of cyanoaquacobyrinic acid cytotoxic effects on tumor cells with experimental confirmation on BT-474 and A549 cell Abstract  similar documents
I. Yu. Torshin, M. V. Filimonova, O. A. Gromova, L. A. Maiorova, M. A. Sorokina, D. E. Frolova, A. N. Gromov, I. A. Reyer
"... the evaluation of the action of candidate molecules on various types of tumor cells. Vitamin B12 and its ..."
 
Online First Biosensors for measuring nitric oxide NO levels in biosubstrates: a systematic analysis Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, L. A. Mayorova, A. N. Gromov
"... Nitric oxide NO is a signaling molecule involved in numerous physical and pathological processes ..."
 
Vol 8, No 4 (2015) CLINICAL AND ECONOMIC EVALUATION OF THROMBOPOIETIN RECEPTOR AGONISTS IN THE TREATMENT OF CHRONIC IDIOPATHIC THROMBOCYTOPENIC PURPURA IN ADULTS Abstract  similar documents
E. A. Pyadushkina, M. Yu. Frolov, M. V. Avksentyeva
"... Aim. Hospital-based economic analysis for the use of thrombopoietin receptor agonists (TRA ..."
 
Online First Osteoarthritis therapy misconcepts Abstract  similar documents
O. A. Shavlovskaya, О. А. Gromova, I. Yu. Torshin, I. D. Romanov
"... , as new molecules appear, data concerning drugs/molecules that are already in use, appear as well ..."
 
Vol 16, No 2 (2023) From misconceptions to reasonable osteoarthritis patients therapy Abstract  similar documents
O. A. Shavlovskaya, О. А. Gromova, I. Yu. Torshin, I. D. Romanov
"... revised, as new molecules appear, data on drugs/molecules already in use, including data on adverse events ..."
 
Vol 5, No 2 (2012) COST EFFECTIVENESS OF ORAL PERICALCITOL IN PATIENTS WITH STAGE III-IV CHRONIC KIDNEY DISEASE AND SECONDARY HYPERPARATHYREOSIS Abstract  similar documents
A. V. Rudakova
"... results of clinical trials demonstrate that selective vitamin D receptor agonist ..."
 
Vol 13, No 3 (2020) Chemomicrobiomic analysis of glucosamine sulfate, prebiotics and non-steroidal anti-inflammatory drugs Abstract  similar documents
O. A. Gromova, I. Yu. Torshin, A. V. Naumov, V. A. Maksimov
"... , fructose) as molecules of comparison. For each substance, estimates of the area under the curve (AUC) were ..."
 
Vol 12, No 1 (2019) Evaluation of the clinical efficacy of anti-asthma pharmacotherapy in children using the software package based on the Fishburn method Abstract  similar documents
O. V. Zhukova, I. V. Nikiforova
"... -acting β2- agonists (SABA) and antagonists of leukotriene receptors (ALR), the combination of IGCS, long ..."
 
Vol 14, No 2 (2021) Chemoreactome screening of pharmaceutical effects on SARS-CoV-2 and human virome to help decide on drug-based COVID-19 therapy Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, A. G. Chuchalin, Yu. I. Zhuravlev
"... proteins and/or function as adaptogenic molecules that improve the functioning of cells exposed to viral ..."
 
Vol 9, No 3 (2016) EFFICACY AND SAFETY OF THE ORAL ANTICOAGULANTS IN THE MANAGEMENT OF VENOUS THROMBOEMBOLISM: INDIRECT COMPARISON Abstract  similar documents
V. I. Petrov, O. V. Shatalova, V. S. Gorbatenko, D. V. Frolov, E. A. Ponomarev, A. S. Maslakov
"... . Dabigatran increased major bleeding risk compared to apixaban RR=2.36; 95% CI 1.15-4.82 and the risk major ..."
 
Vol 14, No 2 (2021) Comparative effectiveness of simultaneous and staged operations in patients with atherosclerotic lesions of carotid and coronary arteries Abstract  similar documents
A. B. Ismoilova, N. M.U. Sultanbaeva, A. A. Abdurakhmanov, Sh. Z. Umarova, D. Kh. Dzhalalova, S. Ch. Dzhalalov
"... myocardial infarction was RR 0.13 (95% CI 0.02–0.67) for simultaneous tactics, and RR 7.79 (95% CI 1.5–40 ..."
 
Vol 9, No 1 (2016) SYSTEMATIC REVIEW OF PENTAGLOBIN EFFICACY IN PREVENTING MORTALITY IN NEWBORNS AND OLDER CHILDREN WITH BACTERIAL INFECTIONS AND SEPSIS Abstract  similar documents
V. K. Fedyaeva, O. Yu. Rebrova
"... groups, RR 0.51 [0.32; 0.82], and in BT with or without placebo, RR 0.56 [0.34; 0.91]. Children under 24 ..."
 
Vol 16, No 2 (2023) Analysis of social and economic aspects of using prolonged forms of opioid analgesics for the treatment of chronic pain syndrome in cancer patients Abstract  similar documents
E. A. Pyadushkina, E. V. Derkach, A. V. Palekhov
"... of achieving pain control – risk ratio (RR) 0.88 (95% confidence interval (CI) 0.78–1.00), frequency of using ..."
 
Vol 16, No 4 (2023) Pharmacoeconomic analysis of using empegfilgrastim for the treatment of early and locally advanced HER2+ breast cancer in the Russian Federation Abstract  similar documents
M. V. Zhuravleva, K. A. Kokushkin, E. A. Luchinin, E. V. Luchinina, T. R. Kameneva, E. V. Kuznetsova, V. S. Krysanova, E. V. Makarova, L. G. Zhukova
"... neutropenia in patients with early and locally advanced human epidermal growth factor receptor 2 positive (HER ..."
 
Vol 15, No 1 (2022) Perioperative pharmacotherapy for endoprosthetics: potential of chondroitin sulfate and glucosamine sulfate Abstract  similar documents
I. Yu. Torshin, T. B. Minasov, N. V. Zagorodniy, A. M. Lila, O. A. Gromova
"... and glucosamine sulfate includes inhibition of NF-κB cascade, toll-like receptors, pro-inflammatory cytokines ..."
 
Vol 12, No 4 (2019) Pharmacoeconomic analysis of using cyclin-dependent kinase 4 and 6 inhibitors in the first line treatment of HR-positive HER2-negative advanced breast cancer Abstract  similar documents
N. A. Avxentyev, E. V. Lubennikova, M. Yu. Frolov
"... are the new treatment options for postmenopausal women with locally advanced or metastatic hormone-receptor ..."
 
Vol 15, No 3 (2022) Prospects for the use of chondroitin sulfate and glucosamine sulfate in the treatment of patients with obesity-associated osteoarthritis (metabolic syndrome) Abstract  similar documents
I. Yu. Torshin, О. A. Gromova, A. M. Lila
"... , was established. Excessive activity of toll receptors, the NF-κB cascade, and metabolic disorders of endogenous ..."
 
Vol 16, No 3 (2023) Clinical and economic assessment of feasibility of using quadritherapy in patients with reduced ejection fraction chronic heart failure in medical organizations of the Moscow Region Abstract  similar documents
A. D. Ermolaeva, T. N. Ermolaeva, K. A. Kokushkin
"... with angiotensin-converting enzyme inhibitors, beta-blockers, and mineralocorticoid-receptor antagonists ..."
 
Vol 16, No 4 (2023) Oncoprotective effects of chondroprotectors: glucosamine, chondroitin sulfate and undenatured type II collagen Abstract  similar documents
I. Yu. Torshin, A. G. Chuchalin, O. A. Gromova
"... inhibition of the pro-inflammatory cascade of tumor necrosis factor alpha, CD44 receptor and nuclear factor ..."
 
Vol 15, No 1 (2022) Application of chondroprotective agents to inhibit osteodestructive processes in the subchondral bone in patients with osteoarthritis Abstract  PDF (Eng)  similar documents
О. А. Gromova, А. М. Lila, I. Yu. Torshin, I. А. Reier
"... the activity of anti-inflammatory cytokines (NF-κB and toll-receptors), stimulate the activity of osteoblasts ..."
 
Vol 16, No 4 (2023) Nephroprotective peptides of Laennec® in the context of pharmacotherapy for nephro-hepato-metabolic disorders Abstract  similar documents
O. A. Gromova, I. Yu. Torshin, A. N. Gromov, O. V. Tikhonova
"... receptors (PDGFR, TGFB1I1). Conclusion. By inhibiting the listed target proteins, HPH peptides provide ..."
 
Vol 18, No 1 (2025) Problems of using phenol (hydroxybenzene) and parabens as pharmaceutical stabilizers: analysis using machine learning methods Abstract  similar documents
I. Yu. Torshin, O. A. Gromova
"... ) effects on estrogen sulfotransferases, (2) direct interactions with estrogen receptors, (3) influence ..."
 
Vol 10, No 2 (2017) CLINICAL AND ECONOMIC EVALUATION OF CHRONIC DISEASE TREATMENT: A DISCREPANCY BETWEEN THE TRADITIONAL PHARMACOECONOMIC AND SOCIO-ECONOMIC ANALYSES Abstract  similar documents
O. V. Zhukova, S. V. Kononova
"... . The addition of montelukast (a leukotriene receptor antagonist) in the treatment regimen leads to an increase ..."
 
Vol 14, No 1 (2021) Analysis of acquisition and the monthly cost of antihypertensive therapy with modern fixed-dose combinations in the Far Eastern Federal District Abstract  similar documents
M. S. Soboleva, E. E. Loskutova
"... II receptor blockers+diuretic/calcium channel blockers: valsartan+amlodipine with a monthly cost ..."
 
Vol 15, No 1 (2022) The analysis of the consumption level of antihypertensive drugs and statins in a retail pharmacy of the Samara Region in 2015–2020 Abstract  similar documents
I. K. Petrukhina, P. A. Lebedev, E. P. Gladunova, T. K. Ryazanova, A. A. Garanin, P. R. Blinkova
"... , angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, calcium channel blockers, β ..."
 
Vol 17, No 4 (2024) Economic effectiveness of fixed-dose combination of alogliptin and pioglitazone in diabetes mellitus treatment Abstract  similar documents
S. К. Zyryanov, I. N. Dyakov
"... of alogliptin-pioglitazone combination versus glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Material ..."
 
Vol 15, No 3 (2022) Long-term analysis of сanagliflozin budget impact in adult patients with type 2 diabetes mellitus and diabetic nephropathy in the Russian Federation Abstract  similar documents
N. A. Avxentyev, Yu. V. Makarova
"... state procurement of SGLT2 inhibitors and glucagon-like peptide-1 receptor agonists in 2021, we ..."
 
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