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Issue | Title | |
Online First | Differential chemoproteomic analysis of RRS-1 candidate molecule and molecules of several nonsteroidal anti-inflammatory drugs | Abstract similar documents |
P. A. Galenko-Yaroshevsky, I. Yu. Torshin, A. N. Gromov, O. A. Gromova, K. F. Suzdalev, R. A. Murashko, A. V. Zelenskaya, A. V. Zadorozhniy, T. R. Glechyan, G. V. Simavonyan, E. M.I. Muhammad | ||
"... of candidate molecule RRS-1 (N-{(Z)-2-(1-methyl-1H-indol-3-yl)-1-[(propylamino)carbonyl]vinyl}benzamide) from ..." | ||
Vol 17, No 3 (2024) | Differential chemoproteomic analysis of RRS-1 candidate molecule and molecules of several nonsteroidal anti-inflammatory drugs | Abstract similar documents |
P. A. Galenko-Yaroshevsky, I. Yu. Torshin, A. N. Gromov, O. A. Gromova, K. F. Suzdalev, R. A. Murashko, A. V. Zelenskaya, A. V. Zadorozhniy, T. R. Glechyan, G. V. Simavonyan, E.M. I. Muhammad | ||
"... of candidate molecule RRS-1 (N-{(Z)-2-(1-methyl-1H-indol-3-yl)1-[(propylamino)carbonyl]vinyl}benzamide) from ..." | ||
Vol 17, No 2 (2024) | Lignan 7-hydroxymatairesinol in the context of post-genomic pharmacology | Abstract similar documents |
А. N. Rubashkina, I. Yu. Torshin, O. A. Gromova, A. N. Galustyan | ||
"... it possible to assess the effect of drugs on genome transcription (transcriptome) and on the proteome ..." | ||
Vol 17, No 3 (2024) | Chemoproteomic analysis of the pharmacological properties of vitamin В12 derivatives | Abstract similar documents |
I. Yu. Torshin, O. A. Gromova, I. A. Dereven’kov, L. A. Maiorova | ||
"... of heptaethanolamine, heptaethylenediamine, heptamethyl and heptabutyl cobyrinates) with human proteome proteins ..." | ||
Vol 17, No 4 (2024) | Chemoreactome prediction of anti-inflammatory, analgesic, ulcerogenic effects of the candidate molecule N-allylimidazole-zinc in comparison with zinc derivatives of nonsteroidal anti-inflammatory drugs | Abstract similar documents |
P. A. Galenko-Yaroshevsky, A. V. Sergeeva, I. Yu. Torshin, A. N. Gromov, I. A. Reyer, O. A. Gromova, B. A. Trofimov, L. N. Parshina, R. A. Murashko, A. V. Zadorozhniy, A. V. Zelenskaya, N. S. Sergeev, Yu. V. Tovkach, O. N. Gulevskaya, I. V. Sholl | ||
"... with the inhibition of kinin receptors, weak antihistaminic and antinociceptive properties. The molecule may exhibit ..." | ||
Vol 18, No 1 (2025) | Systematic analysis of molecules regulating nitric oxide (NO) metabolism and vascular endothelium condition | Abstract similar documents |
I. Yu. Torshin, A. G. Chuchalin, O. A. Gromova | ||
"... Background. Nitric monooxide (NO) is a signaling molecule that plays an important role in many ..." | ||
Vol 15, No 1 (2022) | Efficacy of targeted drugs for the treatment of adults with moderate-to-severe plaque psoriasis in the Russian Federation: a systematic literature review update | Abstract similar documents |
V. D. Sokolova, N. A. Sableva, V. V. Mladov, D. G. Tolkacheva | ||
"... (TNFα) inhibitors (INF, ADA, ETN), small molecules (TOFA and APR), and IL-12/23 inhibitor UST, while NTK ..." | ||
Vol 14, No 4 (2021) | Prospects of using chondroprotectors for the treatment of pulmonary pathology | Abstract similar documents |
I. Yu. Torshin, O. A. Gromova, A. G. Chuchalin | ||
"... -receptors, increased levels of cytokines, degranulation of mast cells, etc.) by CS and GS provide ..." | ||
Vol 15, No 2 (2022) | Biophysical modeling indicates a high affinity of ethyl esters of omega-3 polyunsaturated fatty acids to the enzymes of the pro-inflammatory arachidonic acid cascade | Abstract similar documents |
I. Yu. Torshin, O. A. Gromova | ||
"... at various initial positions of the molecule relative to the receptor pocket and the molecular energy ..." | ||
Vol 17, No 4 (2024) | Proteomic analysis of synergetic neuroprotective effect of adenosine, thiamine, niacin and cyanocobalamin in pathophysiology of diabetic polyneuropathy | Abstract similar documents |
O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok | ||
"... and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular ..." | ||
Vol 17, No 2 (2024) | Chemoreactomic study of fonturacetam effects: molecular mechanisms of influence on adipose tissue metabolism | Abstract similar documents |
O. A. Gromova, I. Yu. Torshin | ||
"... and methods. Chemoreactomic, pharmacoinformatic and chemoneurocytological methods of molecule properties ..." | ||
Vol 16, No 1 (2023) | Modern biomarkers of acute kidney injury | Abstract similar documents |
D. I. Korabelnikov, M. O. Magomedaliev | ||
"... -microglobulin, kidney injury molecule-1, fatty acid binding protein) over the conventional glomerular filtration ..." | ||
Vol 18, No 2 (2025) | Chemoreactomic analysis of the drug prototype pilim-1 in comparison with zinc derivatives of nonsteroidal anti-inflammatory drugs | Abstract similar documents |
P. A. Galenko-Yaroshevsky, I. Y. Torshin, A. N. Gromov, I. A. Reyer, O. A. Gromova, B. A. Trofimov, L. N. Parshina, R. A. Murashko, O. V. Shelemekh, A. V. Zadorozhniy, V. L. Popkov, A. V. Zelenskaya, I. B. Nektarevskaya, A. V. Sergeeva, A. V. Uvarov, Yu. V. Tovkach, I. V. Sholl | ||
"... the need to explore new molecule candidates with reduced ulcerogenic effects. The zinc-containing molecule ..." | ||
Vol 17, No 1 (2024) | Chemoreactomic analysis of acyzole in comparison with zinc derivatives of nonsteroidal anti-inflammatory drugs | Abstract similar documents |
P. A. Galenko-Yaroshevsky, I. Yu. Torshin, A. N. Gromov, O. A. Gromova, R. A. Murashko, A. V. Zelenskaya, L. O. Alukhanyan, O. V. Shelemekh | ||
"... molecules with the structures of millions of other molecules with established molecular pharmacological ..." | ||
Vol 16, No 4 (2023) | Comparative chemomicrobiomic analysis of bacteriocins | Abstract similar documents |
I. Yu. Torshin, O. A. Gromova | ||
"... bacteria). Results. Compared to other molecules, bacteriocin C was characterized by lower MIC constants ..." | ||
Vol 18, No 1 (2025) | Chemoinformatic study of spiramycin in comparison with other antibiotics | Abstract similar documents |
O. A. Gromovа, I. Yu. Torshin | ||
"... the spiramycin molecule and the comparison molecules in terms of efficacy, safety and mechanisms of action ..." | ||
Vol 17, No 3 (2024) | Chemoreactomic analysis of the antioxidant properties of vitamin B12 derivatives | Abstract similar documents |
I. Yu. Torshin, O. A. Gromova, L. A. Maiorova | ||
"... and pharmacological properties. The development of methods for predicting the properties of these molecules based ..." | ||
Vol 16, No 3 (2023) | The prospects for the use of vitamin B12 derivatives in pharmacology | Abstract similar documents |
I. Yu. Torshin, O. A. Gromova, L. A. Maiorova | ||
"... , and the effects of interactions of these modified corrins with “small” inorganic and organic molecules ..." | ||
Vol 17, No 1 (2024) | Chemoreactome screening of aquacobalamin and heptamethyl ester of cyanoaquacobyrinic acid cytotoxic effects on tumor cells with experimental confirmation on BT-474 and A549 cell | Abstract similar documents |
I. Yu. Torshin, M. V. Filimonova, O. A. Gromova, L. A. Maiorova, M. A. Sorokina, D. E. Frolova, A. N. Gromov, I. A. Reyer | ||
"... the evaluation of the action of candidate molecules on various types of tumor cells. Vitamin B12 and its ..." | ||
Online First | Biosensors for measuring nitric oxide NO levels in biosubstrates: a systematic analysis | Abstract similar documents |
I. Yu. Torshin, O. A. Gromova, L. A. Mayorova, A. N. Gromov | ||
"... Nitric oxide NO is a signaling molecule involved in numerous physical and pathological processes ..." | ||
Vol 8, No 4 (2015) | CLINICAL AND ECONOMIC EVALUATION OF THROMBOPOIETIN RECEPTOR AGONISTS IN THE TREATMENT OF CHRONIC IDIOPATHIC THROMBOCYTOPENIC PURPURA IN ADULTS | Abstract similar documents |
E. A. Pyadushkina, M. Yu. Frolov, M. V. Avksentyeva | ||
"... Aim. Hospital-based economic analysis for the use of thrombopoietin receptor agonists (TRA ..." | ||
Online First | Osteoarthritis therapy misconcepts | Abstract similar documents |
O. A. Shavlovskaya, О. А. Gromova, I. Yu. Torshin, I. D. Romanov | ||
"... , as new molecules appear, data concerning drugs/molecules that are already in use, appear as well ..." | ||
Vol 16, No 2 (2023) | From misconceptions to reasonable osteoarthritis patients therapy | Abstract similar documents |
O. A. Shavlovskaya, О. А. Gromova, I. Yu. Torshin, I. D. Romanov | ||
"... revised, as new molecules appear, data on drugs/molecules already in use, including data on adverse events ..." | ||
Vol 5, No 2 (2012) | COST EFFECTIVENESS OF ORAL PERICALCITOL IN PATIENTS WITH STAGE III-IV CHRONIC KIDNEY DISEASE AND SECONDARY HYPERPARATHYREOSIS | Abstract similar documents |
A. V. Rudakova | ||
"... results of clinical trials demonstrate that selective vitamin D receptor agonist ..." | ||
Vol 13, No 3 (2020) | Chemomicrobiomic analysis of glucosamine sulfate, prebiotics and non-steroidal anti-inflammatory drugs | Abstract similar documents |
O. A. Gromova, I. Yu. Torshin, A. V. Naumov, V. A. Maksimov | ||
"... , fructose) as molecules of comparison. For each substance, estimates of the area under the curve (AUC) were ..." | ||
Vol 12, No 1 (2019) | Evaluation of the clinical efficacy of anti-asthma pharmacotherapy in children using the software package based on the Fishburn method | Abstract similar documents |
O. V. Zhukova, I. V. Nikiforova | ||
"... -acting β2- agonists (SABA) and antagonists of leukotriene receptors (ALR), the combination of IGCS, long ..." | ||
Vol 14, No 2 (2021) | Chemoreactome screening of pharmaceutical effects on SARS-CoV-2 and human virome to help decide on drug-based COVID-19 therapy | Abstract similar documents |
I. Yu. Torshin, O. A. Gromova, A. G. Chuchalin, Yu. I. Zhuravlev | ||
"... proteins and/or function as adaptogenic molecules that improve the functioning of cells exposed to viral ..." | ||
Vol 9, No 3 (2016) | EFFICACY AND SAFETY OF THE ORAL ANTICOAGULANTS IN THE MANAGEMENT OF VENOUS THROMBOEMBOLISM: INDIRECT COMPARISON | Abstract similar documents |
V. I. Petrov, O. V. Shatalova, V. S. Gorbatenko, D. V. Frolov, E. A. Ponomarev, A. S. Maslakov | ||
"... . Dabigatran increased major bleeding risk compared to apixaban RR=2.36; 95% CI 1.15-4.82 and the risk major ..." | ||
Vol 14, No 2 (2021) | Comparative effectiveness of simultaneous and staged operations in patients with atherosclerotic lesions of carotid and coronary arteries | Abstract similar documents |
A. B. Ismoilova, N. M.U. Sultanbaeva, A. A. Abdurakhmanov, Sh. Z. Umarova, D. Kh. Dzhalalova, S. Ch. Dzhalalov | ||
"... myocardial infarction was RR 0.13 (95% CI 0.02–0.67) for simultaneous tactics, and RR 7.79 (95% CI 1.5–40 ..." | ||
Vol 9, No 1 (2016) | SYSTEMATIC REVIEW OF PENTAGLOBIN EFFICACY IN PREVENTING MORTALITY IN NEWBORNS AND OLDER CHILDREN WITH BACTERIAL INFECTIONS AND SEPSIS | Abstract similar documents |
V. K. Fedyaeva, O. Yu. Rebrova | ||
"... groups, RR 0.51 [0.32; 0.82], and in BT with or without placebo, RR 0.56 [0.34; 0.91]. Children under 24 ..." | ||
Vol 16, No 2 (2023) | Analysis of social and economic aspects of using prolonged forms of opioid analgesics for the treatment of chronic pain syndrome in cancer patients | Abstract similar documents |
E. A. Pyadushkina, E. V. Derkach, A. V. Palekhov | ||
"... of achieving pain control – risk ratio (RR) 0.88 (95% confidence interval (CI) 0.78–1.00), frequency of using ..." | ||
Vol 16, No 4 (2023) | Pharmacoeconomic analysis of using empegfilgrastim for the treatment of early and locally advanced HER2+ breast cancer in the Russian Federation | Abstract similar documents |
M. V. Zhuravleva, K. A. Kokushkin, E. A. Luchinin, E. V. Luchinina, T. R. Kameneva, E. V. Kuznetsova, V. S. Krysanova, E. V. Makarova, L. G. Zhukova | ||
"... neutropenia in patients with early and locally advanced human epidermal growth factor receptor 2 positive (HER ..." | ||
Vol 15, No 1 (2022) | Perioperative pharmacotherapy for endoprosthetics: potential of chondroitin sulfate and glucosamine sulfate | Abstract similar documents |
I. Yu. Torshin, T. B. Minasov, N. V. Zagorodniy, A. M. Lila, O. A. Gromova | ||
"... and glucosamine sulfate includes inhibition of NF-κB cascade, toll-like receptors, pro-inflammatory cytokines ..." | ||
Vol 12, No 4 (2019) | Pharmacoeconomic analysis of using cyclin-dependent kinase 4 and 6 inhibitors in the first line treatment of HR-positive HER2-negative advanced breast cancer | Abstract similar documents |
N. A. Avxentyev, E. V. Lubennikova, M. Yu. Frolov | ||
"... are the new treatment options for postmenopausal women with locally advanced or metastatic hormone-receptor ..." | ||
Vol 15, No 3 (2022) | Prospects for the use of chondroitin sulfate and glucosamine sulfate in the treatment of patients with obesity-associated osteoarthritis (metabolic syndrome) | Abstract similar documents |
I. Yu. Torshin, О. A. Gromova, A. M. Lila | ||
"... , was established. Excessive activity of toll receptors, the NF-κB cascade, and metabolic disorders of endogenous ..." | ||
Vol 16, No 3 (2023) | Clinical and economic assessment of feasibility of using quadritherapy in patients with reduced ejection fraction chronic heart failure in medical organizations of the Moscow Region | Abstract similar documents |
A. D. Ermolaeva, T. N. Ermolaeva, K. A. Kokushkin | ||
"... with angiotensin-converting enzyme inhibitors, beta-blockers, and mineralocorticoid-receptor antagonists ..." | ||
Vol 16, No 4 (2023) | Oncoprotective effects of chondroprotectors: glucosamine, chondroitin sulfate and undenatured type II collagen | Abstract similar documents |
I. Yu. Torshin, A. G. Chuchalin, O. A. Gromova | ||
"... inhibition of the pro-inflammatory cascade of tumor necrosis factor alpha, CD44 receptor and nuclear factor ..." | ||
Vol 15, No 1 (2022) | Application of chondroprotective agents to inhibit osteodestructive processes in the subchondral bone in patients with osteoarthritis | Abstract PDF (Eng) similar documents |
О. А. Gromova, А. М. Lila, I. Yu. Torshin, I. А. Reier | ||
"... the activity of anti-inflammatory cytokines (NF-κB and toll-receptors), stimulate the activity of osteoblasts ..." | ||
Vol 16, No 4 (2023) | Nephroprotective peptides of Laennec® in the context of pharmacotherapy for nephro-hepato-metabolic disorders | Abstract similar documents |
O. A. Gromova, I. Yu. Torshin, A. N. Gromov, O. V. Tikhonova | ||
"... receptors (PDGFR, TGFB1I1). Conclusion. By inhibiting the listed target proteins, HPH peptides provide ..." | ||
Vol 18, No 1 (2025) | Problems of using phenol (hydroxybenzene) and parabens as pharmaceutical stabilizers: analysis using machine learning methods | Abstract similar documents |
I. Yu. Torshin, O. A. Gromova | ||
"... ) effects on estrogen sulfotransferases, (2) direct interactions with estrogen receptors, (3) influence ..." | ||
Vol 10, No 2 (2017) | CLINICAL AND ECONOMIC EVALUATION OF CHRONIC DISEASE TREATMENT: A DISCREPANCY BETWEEN THE TRADITIONAL PHARMACOECONOMIC AND SOCIO-ECONOMIC ANALYSES | Abstract similar documents |
O. V. Zhukova, S. V. Kononova | ||
"... . The addition of montelukast (a leukotriene receptor antagonist) in the treatment regimen leads to an increase ..." | ||
Vol 14, No 1 (2021) | Analysis of acquisition and the monthly cost of antihypertensive therapy with modern fixed-dose combinations in the Far Eastern Federal District | Abstract similar documents |
M. S. Soboleva, E. E. Loskutova | ||
"... II receptor blockers+diuretic/calcium channel blockers: valsartan+amlodipine with a monthly cost ..." | ||
Vol 15, No 1 (2022) | The analysis of the consumption level of antihypertensive drugs and statins in a retail pharmacy of the Samara Region in 2015–2020 | Abstract similar documents |
I. K. Petrukhina, P. A. Lebedev, E. P. Gladunova, T. K. Ryazanova, A. A. Garanin, P. R. Blinkova | ||
"... , angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, calcium channel blockers, β ..." | ||
Vol 17, No 4 (2024) | Economic effectiveness of fixed-dose combination of alogliptin and pioglitazone in diabetes mellitus treatment | Abstract similar documents |
S. К. Zyryanov, I. N. Dyakov | ||
"... of alogliptin-pioglitazone combination versus glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Material ..." | ||
Vol 15, No 3 (2022) | Long-term analysis of сanagliflozin budget impact in adult patients with type 2 diabetes mellitus and diabetic nephropathy in the Russian Federation | Abstract similar documents |
N. A. Avxentyev, Yu. V. Makarova | ||
"... state procurement of SGLT2 inhibitors and glucagon-like peptide-1 receptor agonists in 2021, we ..." | ||
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