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FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology

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Vol 17, No 2 (2024) Chemoreactomic study of fonturacetam effects: molecular mechanisms of influence on adipose tissue metabolism Abstract  similar documents
O. A. Gromova, I. Yu. Torshin
"... and methods. Chemoreactomic, pharmacoinformatic and chemoneurocytological methods of molecule properties ..."
 
Vol 17, No 3 (2024) Chemoreactomic analysis of the antioxidant properties of vitamin B12 derivatives Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, L. A. Maiorova
"... and pharmacological properties. The development of methods for predicting the properties of these molecules based ..."
 
Vol 17, No 1 (2024) Chemoreactomic analysis of acyzole in comparison with zinc derivatives of nonsteroidal anti-inflammatory drugs Abstract  similar documents
P. A. Galenko-Yaroshevsky, I. Yu. Torshin, A. N. Gromov, O. A. Gromova, R. A. Murashko, A. V. Zelenskaya, L. O. Alukhanyan, O. V. Shelemekh
"... chemoreactomic modeling of the pharmacological effects of acyzole and zinc derivatives of well-known NSAIDs ..."
 
Online First Chemoreactomic analysis of the drug prototype рilim-1 in comparison with zinc derivatives of nonsteroidal anti-inflammatory drugs Abstract  similar documents
P. A. Galenko-Yaroshevsky, I. Y. Torshin, A. N. Gromov, I. A. Reyer, O. A. Gromova, B. A. Trofimov, L. N. Parshina, R. A. Murashko, O. V. Shelemekh, A. V. Zadorozhniy, V. L. Popkov, A. V. Zelenskaya, I. B. Nektarevskaya, A. V. Sergeeva, A. V. Uvarov, Yu. V. Tovkach, I. V. Sholl
"... to explore new candidate molecules with reduced ulcerogenic effects. The zinc-containing molecule-candidate ..."
 
Vol 17, No 3 (2024) Differential chemoproteomic analysis of RRS-1 candidate molecule and molecules of several nonsteroidal anti-inflammatory drugs Abstract  similar documents
P. A. Galenko-Yaroshevsky, I. Yu. Torshin, A. N. Gromov, O. A. Gromova, K. F. Suzdalev, R. A. Murashko, A. V. Zelenskaya, A. V. Zadorozhniy, T. R. Glechyan, G. V. Simavonyan, E.M. I. Muhammad
"... .6). Conclusion. Chemoreactomic and chemoproteomic profiling of RRS-1 candidate molecule provided pre-experimental ..."
 
Online First Differential chemoproteomic analysis of RRS-1 candidate molecule and molecules of several nonsteroidal anti-inflammatory drugs Abstract  similar documents
P. A. Galenko-Yaroshevsky, I. Yu. Torshin, A. N. Gromov, O. A. Gromova, K. F. Suzdalev, R. A. Murashko, A. V. Zelenskaya, A. V. Zadorozhniy, T. R. Glechyan, G. V. Simavonyan, E. M.I. Muhammad
"... .6). Conclusion. Chemoreactomic and chemoproteomic profiling of RRS-1 candidate molecule provided pre-experimental ..."
 
Vol 17, No 4 (2024) Chemoreactome prediction of anti-inflammatory, analgesic, ulcerogenic effects of the candidate molecule N-allylimidazole-zinc in comparison with zinc derivatives of nonsteroidal anti-inflammatory drugs Abstract  similar documents
P. A. Galenko-Yaroshevsky, A. V. Sergeeva, I. Yu. Torshin, A. N. Gromov, I. A. Reyer, O. A. Gromova, B. A. Trofimov, L. N. Parshina, R. A. Murashko, A. V. Zadorozhniy, A. V. Zelenskaya, N. S. Sergeev, Yu. V. Tovkach, O. N. Gulevskaya, I. V. Sholl
"... to cyclooxygenase-1 inhibition. The zinc-containing candidate molecule N-allylimidazole-zinc (bis-(N-allylimidazole ..."
 
Vol 17, No 1 (2024) Chemoreactome screening of aquacobalamin and heptamethyl ester of cyanoaquacobyrinic acid cytotoxic effects on tumor cells with experimental confirmation on BT-474 and A549 cell Abstract  similar documents
I. Yu. Torshin, M. V. Filimonova, O. A. Gromova, L. A. Maiorova, M. A. Sorokina, D. E. Frolova, A. N. Gromov, I. A. Reyer
"... the evaluation of the action of candidate molecules on various types of tumor cells. Vitamin B12 and its ..."
 
Vol 18, No 1 (2025) Systematic analysis of molecules regulating nitric oxide (NO) metabolism and vascular endothelium condition Abstract  similar documents
I. Yu. Torshin, A. G. Chuchalin, O. A. Gromova
"... Background. Nitric monooxide (NO) is a signaling molecule that plays an important role in many ..."
 
Vol 14, No 2 (2021) Chemoreactome screening of pharmaceutical effects on SARS-CoV-2 and human virome to help decide on drug-based COVID-19 therapy Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, A. G. Chuchalin, Yu. I. Zhuravlev
"... proteins and/or function as adaptogenic molecules that improve the functioning of cells exposed to viral ..."
 
Vol 15, No 1 (2022) Efficacy of targeted drugs for the treatment of adults with moderate-to-severe plaque psoriasis in the Russian Federation: a systematic literature review update Abstract  similar documents
V. D. Sokolova, N. A. Sableva, V. V. Mladov, D. G. Tolkacheva
"... (TNFα) inhibitors (INF, ADA, ETN), small molecules (TOFA and APR), and IL-12/23 inhibitor UST, while NTK ..."
 
Vol 16, No 1 (2023) Modern biomarkers of acute kidney injury Abstract  similar documents
D. I. Korabelnikov, M. O. Magomedaliev
"... -microglobulin, kidney injury molecule-1, fatty acid binding protein) over the conventional glomerular filtration ..."
 
Vol 16, No 4 (2023) Comparative chemomicrobiomic analysis of bacteriocins Abstract  similar documents
I. Yu. Torshin, O. A. Gromova
"... bacteria). Results. Compared to other molecules, bacteriocin C was characterized by lower MIC constants ..."
 
Vol 18, No 1 (2025) Chemoinformatic study of spiramycin in comparison with other antibiotics Abstract  similar documents
O. A. Gromovа, I. Yu. Torshin
"... the spiramycin molecule and the comparison molecules in terms of efficacy, safety and mechanisms of action ..."
 
Vol 16, No 3 (2023) The prospects for the use of vitamin B12 derivatives in pharmacology Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, L. A. Maiorova
"... , and the effects of interactions of these modified corrins with “small” inorganic and organic molecules ..."
 
Vol 17, No 4 (2024) Proteomic analysis of synergetic neuroprotective effect of adenosine, thiamine, niacin and cyanocobalamin in pathophysiology of diabetic polyneuropathy Abstract  similar documents
O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok
"... and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular ..."
 
Vol 17, No 3 (2024) Chemoproteomic analysis of the pharmacological properties of vitamin В12 derivatives Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, I. A. Dereven’kov, L. A. Maiorova
"... molecules with 1200 proteins. It was shown that the chemoproteomic profiles of each of the compounds form ..."
 
Online First Biosensors for measuring nitric oxide NO levels in biosubstrates: a systematic analysis Abstract  similar documents
I. Yu. Torshin, O. A. Gromova, L. A. Mayorova, A. N. Gromov
"... Nitric oxide NO is a signaling molecule involved in numerous physical and pathological processes ..."
 
Online First Osteoarthritis therapy misconcepts Abstract  similar documents
O. A. Shavlovskaya, О. А. Gromova, I. Yu. Torshin, I. D. Romanov
"... , as new molecules appear, data concerning drugs/molecules that are already in use, appear as well ..."
 
Vol 16, No 2 (2023) From misconceptions to reasonable osteoarthritis patients therapy Abstract  similar documents
O. A. Shavlovskaya, О. А. Gromova, I. Yu. Torshin, I. D. Romanov
"... revised, as new molecules appear, data on drugs/molecules already in use, including data on adverse events ..."
 
Vol 17, No 2 (2024) Lignan 7-hydroxymatairesinol in the context of post-genomic pharmacology Abstract  similar documents
А. N. Rubashkina, I. Yu. Torshin, O. A. Gromova, A. N. Galustyan
"... of proliferative genes and genes involved in chronic inflammation, the 7(OH)MP molecule inhibits the proliferation ..."
 
Vol 13, No 3 (2020) Chemomicrobiomic analysis of glucosamine sulfate, prebiotics and non-steroidal anti-inflammatory drugs Abstract  similar documents
O. A. Gromova, I. Yu. Torshin, A. V. Naumov, V. A. Maksimov
"... , fructose) as molecules of comparison. For each substance, estimates of the area under the curve (AUC) were ..."
 
Vol 15, No 2 (2022) Biophysical modeling indicates a high affinity of ethyl esters of omega-3 polyunsaturated fatty acids to the enzymes of the pro-inflammatory arachidonic acid cascade Abstract  similar documents
I. Yu. Torshin, O. A. Gromova
"... at various initial positions of the molecule relative to the receptor pocket and the molecular energy ..."
 
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