Analysis of the main indicative values of the pharmaceutical market retail sectors in the constituent entities of the Russian Federation

Objective: to study various typological characteristics of the retail pharmaceutical market sector in 23 constituent entities of the Russian Federation (RF), as well as to analyze the availability of socially important types of pharmaceutical care as of 2021.

Material and methods. The study materials were the data obtained on the basis of specially developed card-queries in the health authorities of constituent entities of the RF, and data from Rosstat, the Federal Antimonopoly Service of the RF, Roszdravnadzor. Methods of comparative, structural, logical and content analysis, as well as the method of data grouping were used. The study included analysis of the overall structure of retail sectors of regional pharmaceutical markets, the structure of pharmacy organizations (POs) depending on the form of ownership, availability of pharmaceutical care to the population of the RF constituent entities, and quantitative characteristics of POs that provide socially important types of pharmaceutical care: extemporaneous compounding of dosage forms, sales of drugs, psychotropic substances and their precursors included in the Lists II and III of the Decree No. 681 of the RF Government of June 30, 1998. Based on the obtained values of the indicative indicators, a typologization of the constituent entities of the RF was carried out.

Results. By the total number of retail sales facilities the top five are regional pharmaceutical markets of Novosibirsk Region (2688), Nizhny Novgorod Region (2265), Samara Region (2493), Tula Region (1516), and Belgorod Region (1383). As of 2021, the share of pharmacies in the total pharmacy retail sector structure of the analyzed regions amounted to 45.5%, pharmacy outlets and kiosks – 54.1% and 0.4%, respectively. In most cases, the pharmaceutical market of constituent entities of the RF was concentrated: the mean value of the mean population per PO indicator was 2,215 persons. The pharmaceutical markets of Tula, Kursk and Pskov Regions are the most concentrated, the markets of Chechen Republic, Murmansk Region and Krasnoyarsk Territory are the least concentrated. The main burden of providing socially significant types of medicines falls on the state and municipal sectors, with the state sector accounting for 11.2% in the total structure of POs.

Conclusion. Based on the study of basic indicators the situation in the pharmaceutical market retail sectors of different constituent entities of the RF was characterized. The revealed in 2021 downward trend in the total number of retail sales facilities may be caused by an excessively high degree of PO concentration on regional markets, as well as a noticeable reduction in the profitability of pharmaceutical activities (including due to a decline in the solvency of the population associated with the spread of a new coronavirus infection) and the impact of legislative changes.

1. Sapir E.V., Karachev I.A. Features of the global pharmaceutical market and the problems of its exploration by Russia's companies. Russian Foreign Economic Journal. 2016; 8: 97–111 (in Russ.).

2. Vorontsova N.A. Nature and specific features of pharmaceutical market. Baikal Research Journal. 2016; 7 (3): 16 (in Russ.). https://doi.org/10.17150/2411-6262.2016.7(3).16.

3. Petrukhina I.К., Yagudina R.I., Ryazanova Т.К., et al. Retail sector of the pharmaceutical market of the Russian Federation: regional characteristics analysis. Remedium. 2019; 10: 8–28 (in Russ.). https://doi.org/10.21518/1561-5936-2019-10-8-28.

4. Pharmaceutical market 2021: ups and downs. Results of 12 months of 2021. Available at: https://clck.ru/rg7ie (in Russ.) (accessed 06.07.2022).

5. Trofimova E.O. Russian pharmaceutical market: in line with global trends. Remedium. 2013; 7-8: 71–8 (in Russ.).

6. Petrukhina I.K., Yagudina R.I., Kurkin V.A. Retail sector of the pharmaceutical market of the Volga Federal District: main trends and characteristics. Samara: Ofort LLC; 2016 (in Russ.).

7. Doguzova V. More than two thousand pharmacies have been opened in Russia in a year. Available at: https://pharmvestnik.ru/content/news/V-Rossii-za-god-otkryli-bolee-dvuh-tysyach-aptek.html (in Russ.) (accessed 03.11.2021).

8. Kotova M. A record low number of new pharmacies opened in Russia last year. Available at: https://www.vedomosti.ru/business/articles/2021/03/05/860308-rossii-proshlom (in Russ.) (accessed 06.07.2022).

9. Prozherina J. Pharmacy drug market in Russia: 2018 results. Remedium. 2019; 1-2: 16–18 (in Russ.). https://doi.org/10.21518/1561-5936-2019-1-2-16-18.

10. Federal State Statistics Service. Regions of Russia. Main characteristics of the subjects of the Russian Federation 2020. Available at: https://rosstat.gov.ru/folder/210/document/13205 (in Russ.) (accessed 06.07.2022).

11. Federal Antimonopoly Service. The results of the analysis of the state of competition in the market of retail trade in medicines, medical products and related products in 2010–2011 within the geographical boundaries of municipal districts and urban districts. Available at: https://fas.gov.ru/documents/575049 (in Russ.) (accessed 03.11.2021).

12. Brooks J.M., Doucette W.R., Wan S., Klepser D.G. Retail pharmacy market structure and performance. Inquiry. 2008; 45 (1): 75–88. https://doi.org/10.5034/inquiryjrnl_45.01.75.

13. Lukyantseva D.V., Mel’nikova L.S., Tatarinov A.P. The international practice of drug supply in the outpatient segment. FARMAKOEKONOMIKA. Sovremennaya farmakoekonomika i farmakoepidemiologiya / FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology. 2017; 10 (4): 44–52 (in Russ.). https://doi.org/10.17749/2070-4909.2017.10.4.044-052.

14. Galkovskaya G. Global pharmacy market. Part one: Infrastructure and key features. Available at: https://www.apteka.ua/article/349023 (in Russ.) (accessed 30.07.2022).

15. Aityan T.V. Comparing the drug provision systems in Europe and the USA. Valuable lessons for Russia. Regional Economics: Theory and Practice. 2018; 16 (4): 624–39 (in Russ.). https://doi.org/10.24891/re.16.4.624.

16. Koblitz S., Schlanger S., Palmer K. Distribution and marketing of drugs in the United States: overview. Available at: https://clck.ru/sS264 (accessed 30.07.2022).

17. Galkovskaya G. Pharmacies and chains in the context of ownership forms. An outline of global trends. Available at: https://www.apteka.ua/article/358592 (in Russ.) (accessed 30.07.2022).

18. Jagadeesan C.T., Wirtz V.J. Geographical accessibility of medicines: a systematic literature review of pharmacy mapping. J Pharm Policy Pract. 2021; 14: 28. https://doi.org/10.1186/s40545-020-00291-7.

19. Vegas R., Poe V., Pinto G.S. Community pharmacy at a glance 2021: regulation, scope of practice, remuneration, and distribution of medicines through community pharmacy premised and other outlets. Available at: https://farmaciavirtuale.it/wp-content/uploads/2021/07/Community-pharmacy-at-a-glance-2021.pdf (accessed 30.07.2022).

20. Gladunova E.P. Ecological aspects of intra pharmaceutical production of medicines. Izvestia of Samara Scientific Center of the Russian Academy of Sciences. 2014; 16 (5-2): 983–6 (in Russ.).

21. Smekhova I.Ye., Ladutko Yu.M., Kalinina O.V. Extemporal manufacture of medicines. problems and solutions. Vestnik farmatsii / Bulletin of Pharmacy. 2021; 1: 48–52 (in Russ.). https://doi.org/10.52540/2074-9457.2021.1.48.

22. Compounding pharmacies market to be worth US$ 13,366.5 Mn by 2025 at a CAGR of 7.5% – Persistence Market Research. Available at: https://www.nsenergybusiness.com/pressreleases/companies/persistence-market-research/presscompounding-pharmacies-market-tobe-worth-us-133665-mn-by-2025-at-a-cagr-of-75-persistence-marketresearch/# (accessed 30.07.2022).

23. U.S. compounding pharmacies market size by pharmacy type (503A, 503B), by sterility (sterile, non-sterile), by product (oral, topical, rectal, parenteral, nasal, ophthalmic, otic), by application (pediatric, adult, geriatric, veterinary), by compounding type (pharmaceutical ingredient alteration [PIA], currently unavailable pharmaceutical manufacturing [CUPM], pharmaceutical dosage alteration [PDA]), by therapeutic area (hormone replacement, pain management, dermatology, specialty drugs, nutritional supplements), industry analysis report, growth potential, price trends, competitive market share & forecast, 2022–2030. Available at: https://www.marketresearch.com/One-Off-Global-Market-Insights-v4130/Compounding-Pharmacies-Size-Pharmacy-Type-31894777/ (accessed 30.07.2022).

24. Dennis A., Wessing T. Distribution and marketing of drugs in the EU: overview. Available at: https://uk.practicallaw.thomsonreuters.com/Document/I2730f2af588211e598dc8b09b4f043e0/View/FullText.html?transitionType=SearchItem&contextData=(sc.Search) (accessed 30.07.2022).

25. Telnova E.A., Zagoruychenko A.A. About state regulation in the Russian pharmaceutical market and problems of drug supply. Modern Organization of Drug Supply. 2020; 7 (3): 11–20 (in Russ.). https://doi.org/10.30809/solo.3.2020.2.