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EVALUATION OF SAFETY OF DRUG THERAPY IN CLINICAL PRACTICE

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Abstract

the present review is devoted to an actual problem of safety of pharmacotherapy in clinical practice; the particular attention is paid to the state of this problem in pediatrics. Information about pharmacovigilance is proposed; criteria of definition, methods of collecting (their advantages and limitations), account and analysis of the adverse reactions of drugs in post-marketing period are described. The off label use of drugs in children and a role of clinical pharmacologist in the adverse reactions of drugs monitoring in a hospital is discussed.

About the Authors

M. N. Kostyleva
Russian Children's Clinical Hospital, Ministry of Health of the Russian Federation, Moscow; The Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation, Moscow
Russian Federation


Yu. B. Belousov
The Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation, Moscow
Russian Federation


A. N. Gratsianskaya
Russian Children's Clinical Hospital, Ministry of Health of the Russian Federation, Moscow; The Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation, Moscow
Russian Federation


S. S. Postnikov
Russian Children's Clinical Hospital, Ministry of Health of the Russian Federation, Moscow; The Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation, Moscow
Russian Federation


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For citation:


Kostyleva M.N., Belousov Y.B., Gratsianskaya A.N., Postnikov S.S. EVALUATION OF SAFETY OF DRUG THERAPY IN CLINICAL PRACTICE. FARMAKOEKONOMIKA. Modern Pharmacoeconomic and Pharmacoepidemiology. 2014;7(1):27-32. (In Russ.)

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