Acute issues in the pharmacotherapy of hand osteoarthritis
https://doi.org/10.17749/2070-4909/farmakoekonomika.2020.067
Abstract
The article focuses on the review of a pharmacotherapeutic approach to the therapy of hand osteoarthritis (HO). Apart from non-steroid antiinflammatory drugs (NSAID), promising therapeutic means of HO therapy include steroid drugs, chondroitin sulfate (CS), glucosamine sulfate (GS), and vitamin D. Transdermal application of NSAID and steroid drugs reduces the side effects without a decrease in the effectiveness of the therapy. Reconstructive therapy of cartilaginous and connective tissue of hands includes a long-term application of CS/GS, and in the acute period, injections of CS/GS.
Keywords
hand osteoarthritis,
steroid and non-steroid anti-inflammatory drugs,
chondroitin sulfate,
glucosamine sulfate,
Chondroguard,
Sustaguard Arthro
Supporting agencies: This work was supported by the RFBR grant No. 18-07-01022
About the Authors
O. A. Gromova
Federal Research Center Computer Sciences and Control, Russian Academy of Sciences; Moscow State University
Russian Federation
Russian Federation
Olga A. Gromova - MD, Dr Sci Med, Professor, Senior Researcher, Scientific Director of the Federal Research Center Computer Sciences and Control, RAS; Leading Researcher, Center for Big Data Analysis, MSU; Scopus Author ID: 7003589812; WoS Researcher ID: J-4946-2017; RSCI SPIN-code: 6317-9833; eLIBRARY ID: 94901.
44-2 Vavilova Str., Moscow 119333; 1 Leninskie gory, Moscow 119991
I. Yu. Torshin
Federal Research Center Computer Sciences and Control, Russian Academy of Sciences; Moscow State University
Russian Federation
Russian Federation
Ivan Yu. Torshin - MD, PhD, Senior Researcher, Federal Research Center Computer Sciences and Control, RAS; Big Data Storage and Analysis Center, MSU; Scopus Author ID: 7003300274; WoS Researcher ID: C-7683-2018; RSCI SPIN-code: 1375-1114; eLIBRARY ID: 54104.
44-2 Vavilova Str., Moscow 119333; 1 Leninskie gory, Moscow 119991
A. V. Naumov
Russian Gerontological Research and Clinical Center, Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Anton V. Naumov - MD, Dr Sci Med, Professor, Head of the laboratory of diseases of the musculoskeletal system of the Russian gerontological scientific clinical center; RSCI SPIN-code: 4763-9738; eLIBRARY ID: 393279.
1 Ostrovityanova Str., Moscow 117997
L. V. Vasilyeva
Burdenko state medical University
Russian Federation
Russian Federation
Lyudmila V. Vasilyeva - MD, Dr Sci Med, Professor, Head of the Department of propaedeutics of internal diseases; RSCI SPIN-code: 7341-8250.
Studencheskaya Str., 10, Voronezh 394036
Ye. F. Yevstratova
Burdenko state medical University
Russian Federation
Russian Federation
Yelizaveta F. Yevstratova - MD, Dr Sci Med, Associate Professor, Department of propaedeutics of internal diseases; RSCI SPIN-code 4293-3559; eLIBRARY ID: 647774.
Studencheskaya Str., 10, Voronezh 394036
А. N. Gromov
Federal Research Center Computer Sciences and Control, Russian Academy of Sciences; Moscow State University
Russian Federation
Russian Federation
Andrey N. Gromov - research engineer of the Federal Research Center Computer Sciences and Control, RAS; Researcher of the Center for Big Data Analysis, MSU; Scopus Author ID: 7102053964; WoS Researcher ID: C-74762018; RSCI SPIN-code: 8034-7910; eLIBRARY ID: 15082.
44-2 Vavilova Str., Moscow 119333; 1 Leninskie gory, Moscow 119991
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Gromova O.A., Torshin I.Yu., Naumov A.V., Vasilyeva L.V., Yevstratova Ye.F., Gromov А.N. Acute issues in the pharmacotherapy of hand osteoarthritis. FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology. 2020;13(4):452-462. (In Russ.) https://doi.org/10.17749/2070-4909/farmakoekonomika.2020.067
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