Effectiveness of preliminary differential diagnosis of benign and malignant skin neoplasms using the Derma Onko Check artificial intelligence program
https://doi.org/10.17749/2070-4909/farmakoekonomika.2025.294
Abstract
Objective: to evaluate the effectiveness of preliminary differential diagnostics of benign and malignant skin tumors during initial medical consultations in primary health care using the Derma Onko Check artificial intelligence (AI) program for electronic computing devices (smartphone application).
Material and methods. The effectiveness of the Derma Onko Check program for visual identification of benign and malignant skin tumors was evaluated in 135 patients aged 22 to 78 years with various skin lesions that appeared visually suspicious for malignancy. The conclusions generated by the program were compared with the results of dermatoscopic and morphological examinations.
Results. The diagnostic accuracy of the Derma Onko Check program in determining the likelihood of a patient having a benign or malignant skin tumor was 96%, sensitivity was 98%, specificity was 96%, the proportion of false-positive results was 4.3%, and the propor
Conclusion. The use of modern AI-based software for electronic computing devices enables early detection of malignant skin tumors during initial examinations in primary health care. This is particularly relevant for medical institutions and regions with a shortage or absence of dermatologists and oncologists.
tion of falsenegative results was 2.4%.
About the Authors
A. I. LamotkinRussian Federation
Andrey I. Lamotkin
5 2nd Brestskaya Str., Moscow 123056
11 Dobrolyubov Str., Moscow 127254
D. I. Korabelnikov
Russian Federation
Daniil I. Korabelnikov, PhD, Assoc. Prof.
5 2nd Brestskaya Str., Moscow 123056
O. Yu. Olisova
Russian Federation
Olga Yu. Olisova, Dr. Sci. Med., Prof., Corr. Member of RAS
8 bldg 2 Trubetskaya Str., Moscow 119048
I. A. Lamotkin
Russian Federation
Igor A. Lamotkin, Dr. Sci. Med., Prof.
3 Gospitalnaya Sq., Moscow 105229,
11 Volokolamskoe Shosse, Moscow 125080
References
1. Ahmadi K., Prickaerts E., Smeets J.G.E., et al. Current approach of skin lesions suspected of malignancy in general practice in the Netherlands: a quantitative overview. J Eur Acad Dermatol Venereol. 2018; 32 (2): 236–41. https://doi.org/10.1111/jdv.14484.
2. Koelink C.J., Kollen B.J., Groenhof F., et al. Skin lesions suspected of malignancy: an increasing burden on general practice. BMC Fam Pract. 2014; 15: 29. https://doi.org/10.1186/1471-2296-15-29.
3. Wakkee M., van Egmond S., Louwman M., et al. Opportunities for improving the efficiency of keratinocyte carcinoma care in primary and specialist care: results from population-based Dutch cohort studies. Eur J Cancer. 2019; 117: 32–40. https://doi.org/10.1016/j.ejca.2019.05.010.
4. van Rijsingen M.C., Vossen R., van Huystee B.E., et al. Skin tumour surgery in primary care: do general practitioners need to improve their surgical skills? Dermatology. 2015; 230 (4): 318–23. https://doi.org/10.1159/000371812.
5. Ferlay J., Colombet M., Soerjomataram I., et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries and 25 major cancers in 2018. Eur J Cancer. 2018; 103: 356–87. https://doi.org/10.1016/j.ejca.2018.07.005.
6. World Cancer Research Fund. Skin cancer statistics. Available at: https://www.wcrf.org/cancer-trends/skin-cancer-statistics (accessed 22.10.2024).
7. Freeman K., Dinnes J., Chuchu N., et al. Algorithm based smartphone apps to assess risk of skin cancer in adults: systematic review of diagnostic accuracy studies. BMJ. 2020; 368: m127. https://doi.org/10.1136/bmj.m127.
8. Harskamp R.E., deVijlder H.C., Bekkenk M.W. Smartphone apps for self-diagnosis of skin cancer. Ned Tijdschr Geneeskd. 2022; 166: D5986 (in Dutch).
9. Kränke T., Tripolt-Droschl K., Röd L., et al. New AI-algorithms on smartphones to detect skin cancer in a clinical setting-A validation study. PLoS One. 2023; 18 (2): e0280670. https://doi.org/10.1371/journal.pone.0280670.
10. Kong F.W., Horsham C., Ngoo A., et al. Review of smartphone mobile applications for skin cancer detection: what are the changes in availability, functionality, and costs to users over time? Int J Dermatol. 2021; 60 (3): 289–308. https://doi.org/10.1111/ijd.15132.
11. Flaten H.K., St Claire C., Schlager E., et al. Growth of mobile applications in dermatology – 2017 update. Dermatol Online J. 2018; 24 (2): 13030/qt3hs7n9z6.
12. Elder D.E., Massi D., Scolyer R.A., Willemze R. (Eds) WHO classification of skin tumors. In: WHO classification of tumors, 4th ed. Vol. 11. International Agency for Research on Cancer; 2018.
13. Lamotkin A.I., Korabelnikov D.I., Lamotkin I.A., et al. Artificial intelligence in healthcare and medicine: the history of key events, its significance for doctors, the level of development in different countries. FARMAKOEKONOMIKA. Sovremennaya farmakoekonomika i farmakoepidemiologiya / FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology. 2024; 17 (2): 243–50 (in Russ.). https://doi.org/10.17749/2070-4909/farmakoekonomika. 2024.254.
14. Lamotkin A.I., Korabelnikov D.I., Lamotkin I.A. Artificial intelligence: basic terms and concepts, the application in healthcare and clinical medicine. FARMAKOEKONOMIKA. Sovremennaya farmakoekonomika i farmakoepidemiologiya / FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology. 2024; 17 (3): 409–15 (in Russ.). https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.267.
15. Buechi R., Faes L., Bachmann L.M., et al. Evidence assessing the diagnostic performance of medical smartphone apps: a systematic review and exploratory meta-analysis. BMJ Open. 2017; 7 (12): e018280. https://doi.org/10.1136/bmjopen-2017-018280.
16. Steeb T., Wessely A., French L.E., et al. Skin cancer smartphone applications for German-speaking patients: review and content analysis using the mobile app rating scale. Acta Derm Venereol. 2019; 99 (11): 1043–4. https://doi.org/10.2340/00015555-3240.
17. Zaar O., Larson A., Polesie S., et al. Evaluation of the diagnostic accuracy of an online artificial intelligence application for skin disease diagnosis. Acta Derm Venereol. 2020; 100 (16): adv00260. https://doi.org/10.2340/00015555-3624.
18. Esteva A., Kuprel B., Novoa R.A., et al. Dermatologist-level classification of skin cancer with deep neural networks. Nature. 2017; 542 (7639): 115–8. https://doi.org/10.1038/nature21056.
19. Han S.S., Kim M.S., Lim W., et al. Classification of the clinical images for benign and malignant cutaneous tumors using a deep learning algorithm. J Invest Dermatol. 2018; 138 (7): 1529–38. https://doi.org/10.1016/j.jid.2018.01.028.
20. Pai V.V., Pai R.B. Artificial intelligence in dermatology and healthcare: an overview. Indian J Dermatol Venereol Leprol. 2021; 87 (4): 457–67. https://doi.org/10.25259/IJDVL_518_19.
Review
For citations:
Lamotkin A.I., Korabelnikov D.I., Olisova O.Yu., Lamotkin I.A. Effectiveness of preliminary differential diagnosis of benign and malignant skin neoplasms using the Derma Onko Check artificial intelligence program. FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology. 2025;18(2):261–270. (In Russ.) https://doi.org/10.17749/2070-4909/farmakoekonomika.2025.294

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.