PHARMACOECONOMIC ANALYSIS OF THE USE OF OXALIPLATIN CHEMOTHERAPY FOR COLORECTAL CANCER.REAL (ACTUAL) CLINICAL PRACTICE DATA
Abstract
to assess the effectiveness of medicines the retrospective observational study of 1343 case of hospitalization (case reports) of 214 colorectal cancer patients treated with oxaliplatin at the St. Petersburg State Health Care Institution «City Clinical Oncology Dispensary» in 2008-2010 was done. Pharmacoeconomic analysis of application of oxaliplatin in colorectal cancer was performed. Cost-effectiveness analysis was used. Calculation of direct medical costs, direct non-medical costs and indirect costs was performed. Three trade names of oxaliplatin was used: eloxatin – 42.2%; platikad – 31.6%; eksorum – 26.2%. Middle cover price of case report
was 252,294 rubles. In average oxaliplatin therapy was effective in 83.1%. ICER for eloxatin was 8,801 and 18,162 compared to eksorum and platikad respectively. As a result it was shown that the treatment with eloxatin was clinical and cost-effective.
About the Authors
A. V. PavlyshRussian Federation
A. S. Kolbin
Russian Federation
A. R. Kasimova
Russian Federation
References
1. Belousov Yu.B. Planning and conduct of clinical trials of medicinal products [Planirovanie i provedenie klinicheskikh issledovanii lekarstvennykh sredstv]. Moscow. 2000; 579 s.
2. Gan'shina I.P., Barsukov Yu.A. Vestnik RONTs im. N.N. Blokhina RAMN. 2006; 17 (3): 5-11.
3. Data on the purchase of the St. Petersburg government health care «City Clinical Oncology Dispensary» [Dannye zakupki Sankt-Peterburgskogo gosudarstvennogo uchrezhdeniya zdravookhraneniya «Gorodskoi klinicheskii onkologicheskii dispanser»]. 2010.
4. Kaprin A.D., Starinskii V.V., Petrova G.V. Malignancies in 2012 (morbidity and mortality) [Zlokachestvennye novoobrazovaniya v 2012 godu (zabolevaemost' i smertnost')]. Moscow. 2013.
5. The Ministry of Health of the Russian Federation. №163 order dated 27.05.2011. Industry standard clinical and economic research. General provisions 91500.14.0001-2002. [Ministerstvo Zdravookhraneniya Rossiiskoi Federatsii. Prikaz №163 ot 27.05.2011. Otraslevoi standart kliniko-ekonomicheskogo issledovaniya. Obshchie polozheniya 91500.14.0001-2002].
6. Yagudina R.I., Kulikov A.Yu., Nguen T. FARMAKOEKONOMIKA. Sovremennaya farmakoekonomika i farmakoepidemiologiya. 2011; 4 (1): 7-12.
7. Gold M., Siegel J.E., Russell L.B., Weinstein M.C. Costeffectiveness in Health and Medicine. New York. 1996. 425 s.
8. http://www.gks.ru
9. Walley T., Haycox A., Boland A. Pharmacoeconomics – Elsevier Health Sciences. 2004. 216 s.
Review
For citations:
Pavlysh A.V., Kolbin A.S., Kasimova A.R. PHARMACOECONOMIC ANALYSIS OF THE USE OF OXALIPLATIN CHEMOTHERAPY FOR COLORECTAL CANCER.REAL (ACTUAL) CLINICAL PRACTICE DATA. FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology. 2014;7(3):26-29. (In Russ.)

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