Prehabilitation strategies in patients with vulvar cancer
https://doi.org/10.17749/2070-4909/farmakoekonomika.2026.366
Abstract
Vulvar cancer, a relatively rare gynecologic oncology condition, remains a pressing issue given its late diagnosis and the significant decline in quality of life following surgery and chemoradiation. A promising approach to improving the quality of medical care for patients with vulvar cancer is the implementation of prehabilitation and rehabilitation programs. Prehabilitation is a set of measures aimed at improving the patients’ physical function and mental state to mitigate the severity of deconditioning, improve treatment outcomes, and enhance their quality of life. Studies conducted to date show that multimodal prehabilitation programs have a positive effect on patients’ functional capacity and both short- and long-term treatment outcomes. The introduction of prehabilitation programs into clinical practice may be an important, undervalued resource for improving the quality of medical care for patients with gynecologic oncology. This review, based on evidence-based medicine, presents current approaches to prehabilitation for patients with vulvar cancer. Particular attention is paid to studies that are currently underway, as their results may advance our understanding of the role of prehabilitation in improving outcomes in gynecologic oncology in real-world clinical practice.
About the Authors
M. A. TishchenkoRussian Federation
Marina A. Tishchenko
27 bldg 1–30 Istra Settlement, Moscow Region, Krasnogorsk Urban District 143515
D. V. Blinov
Russian Federation
Dmitry V. Blinov, Dr. Sci. Med., MBA
WoS ResearcherID: E-8906-2017
Scopus Author ID: 6701744871
37А bldg 1 Altufyevskoe Shosse, Moscow 127410
11-13/1 Lyalin Passage, Moscow 101000
5 2nd Brestskaya Str., Moscow 123056
A. G. Solopova
Russian Federation
Antonina G. Solopova, Dr. Sci. Med., Prof.
WoS ResearcherID: Q-1385-2015
Scopus Author ID: 6505479504
8/2 Trubetskaya Str., Moscow 119048
Yu. V. Mikheeva
Russian Federation
Yulia V. Mikheeva
Scopus Author ID: 57695510300
23 Kashirskoye Shosse, Moscow 115522
A. Yu. Shatilina
Russian Federation
Anastasia Yu. Shatilina
Scopus Author ID: 59334355900
8/2 Trubetskaya Str., Moscow 119048
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What is already known about thе subject?
► Vulvar cancer remains a pressing issue given its late diagnosis and the significant decline in the patients’ quality of life following surgery and chemoradiation
► A promising approach to improving the quality of medical care for patients with vulvar cancer is the implementation of prehabilitation, a set of measures aimed at improving physical function and mental state to mitigate the severity of deconditioning, improve treatment outcomes, and enhance quality of life
What are the new findings?
► This review outlines current approaches to prehabilitation for patients with vulvar cancer based on evidence-based medicine
► Particular attention is paid to the studies carried out at the present moment, the results of which may enhance our understanding of the role of prehabilitation in improving outcomes in gynecologic oncology in real-world clinical practice
How might it impact the clinical practice in the foreseeable future?
► Multimodal prehabilitation programs are capable of optimizing the patients’ functional capacity, having a positive effect on short- and long-term treatment outcomes
► The introduction of prehabilitation programs into clinical practice may be an important, undervalued resource for improving the quality of medical care for patients with gynecologic oncology, including vulvar cancer
Review
For citations:
Tishchenko M.A., Blinov D.V., Solopova A.G., Mikheeva Yu.V., Shatilina A.Yu. Prehabilitation strategies in patients with vulvar cancer. FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology. 2026;19(2):428–434. (In Russ.) https://doi.org/10.17749/2070-4909/farmakoekonomika.2026.366
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