farmaecFARMAKOEKONOMIKA. Modern Pharmacoeconomics and PharmacoepidemiologyФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология2070-49092070-4933IRBIS LLCfarmaec-43Research ArticleMethodologyМетодология фармакоэкономического анализаUsing indirect comparisons in pharmacoeconomic examinationИспользование непрямых сравнений при проведении фармакоэкономической экспертизыБалыкинаЮ. Е.BalykinaYu. E.КолбинА. С.KolbinA. S.ФГБОУ ВПО «Санкт-Петербургский государственный университет»РоссияSaint Petersburg State UniversityRussian FederationГБОУ ВПО СПбГМУ им. И.П. Павлова Минздрава РФ, Санкт-ПетербургРоссияPavlov State Medical University of St. PeterburgRussian Federation2013220320156436Copyright © Balykina Y.E., Kolbin A.S., 20152015Балыкина Ю.Е., Колбин А.С.Balykina Y.E., Kolbin A.S.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pharmacoeconomics.ru/jour/article/view/43

Health technology assessment is a fundamental tool while choosing the most cost- and clinical effective technologies that are being introduced into the health system. The basis for assessment is the data of clinical studies. The experts are interested in not only the effect of a new medical technology, but in its comparison with similar therapeutic approaches. The above is the essence of a comparative study. However, such studies are not common. The article considers the problems associated with the use of indirect comparisons of new medical technologies in the absence of direct comparisons. General recommendations on conducting indirectcomparisons are provided. Possibilities of application of the results obtained in the course of indirect comparisons to conducting pharmacoeconomic analysis are shown.

оценка медицинских технологий является основополагающим инструментом при выборе наиболее целесообразной, с экономических и клинических позиций, технологией, внедряемой в систему здравоохранения. Основой для оценки считают данные клинических исследований. При этом экспертов интересует не просто эффект от новой медицинской технологии, а сравнение ее с подобными лечебными подходами, то есть – сравнительные исследования. Однако, в силу ряда объективных причин, такого рода исследования проводятся далеко не часто. В работе рассматриваются вопросы, связанные с применением непрямых сравнений медицинских технологий при отсутствии прямых сравнений. Приводятся общие рекомендации по методике их проведения. Рассматривается возможность использования результатов, полученных в ходе непрямых сравнений, при проведении фармакоэкономического анализа.

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The authors declare that there are no conflicts of interest present.