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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">farmaec</journal-id><journal-title-group><journal-title xml:lang="en">FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology</journal-title><trans-title-group xml:lang="ru"><trans-title>ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2070-4909</issn><issn pub-type="epub">2070-4933</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2070-4909.2019.12.2.65-71</article-id><article-id custom-type="elpub" pub-id-type="custom">farmaec-288</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ПУБЛИКАЦИИ</subject></subj-group></article-categories><title-group><article-title>Comparative modeling of socio-economic burden among smokers, nonsmokers and former smokers</article-title><trans-title-group xml:lang="ru"><trans-title>Сравнительное моделирование социально-экономического бремени среди курильщиков, некурящих и бросивших курить</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Радченко</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Radchenko</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Радченко Елена Владимировна - аспирант кафедры клинической фармакологии и доказательной медицины.</p><p>Ул. Льва Толстого, д. 6-8, Санкт-Петербург 197022</p></bio><bio xml:lang="en"><p>Elena V. Radchenko - MD, PhD Student, Department of Clinical Pharmacology and Evidence-based Medicine.</p><p>6-8 L’va Tolstogo Str., Saint Petersburg 197022</p></bio><email xlink:type="simple">lena.radchenko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1919-2909</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колбин</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolbin</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Колбин Алексей Сергеевич - доктор медицинских наук, профессор, заведующий кафедрой клинической фармакологии и доказательной медицины, ПСПбГМУ им. академика И.П. Павлова; профессор кафедры фармакологии медицинского факультета СПбГУ; президент Санкт-Петербургского отделения ISPOR (международное общество фармакоэкономических исследований и научного анализа исходов).</p><p>Ул. Льва Толстого, д. 6-8, Санкт-Петербург 197022</p></bio><bio xml:lang="en"><p>Aleksei S. Kolbin - MD, PhD, Professor, Head of the Department of Clinical Pharmacology and Evidence-based Medicine, Pavlov SMU; Professor, Department of Pharmacology, Saint-Petersburg SU; President of the St. Petersburg branch of ISPOR (International Society for Pharmacoeconomic Research and Scientific Analysis of Outcomes).</p><p>6-8 L’va Tolstogo Str., Saint Petersburg 197022</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Pavlov First Saint Petersburg State Medical University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>17</day><month>07</month><year>2019</year></pub-date><volume>12</volume><issue>2</issue><fpage>65</fpage><lpage>71</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Radchenko E.V., Kolbin A.S., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Радченко Е.В., Колбин А.С.</copyright-holder><copyright-holder xml:lang="en">Radchenko E.V., Kolbin A.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pharmacoeconomics.ru/jour/article/view/288">https://www.pharmacoeconomics.ru/jour/article/view/288</self-uri><abstract><sec><title>Aim</title><p>Aim: to assess the socio-economic burden of smoking in the Russian Federation for 2017.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The socio-economic burden was calculated and extrapolated to the entire population of smokers in Russia and then compared with equal sized populations of quitters and non-smokers.</p></sec><sec><title>Results</title><p>Results. In 2017, the burden of tobacco smoking (including the direct costs of medical care and payment for temporary disability, as well as indirect costs - the under-received gross domestic product (GDP) due to temporary disability) was 510.6 billion rubles. The difference between the smokers and the equal-sized non-smoking population is 327.6 billion rubles. The difference between the smokers and the equalsized population of quitters was 216.1 billion rubles.</p></sec><sec><title>Conclusion</title><p>Conclusion. Costs associated with smoking are sizable. Helping quit tobacco smoking (government anti-smoking measures, pharmacotherapy etc.) will not only improve the quality of life and health expectancy of smokers but also save a considerable amount of budget funds.</p></sec></abstract><trans-abstract xml:lang="ru"><p>Цель - оценка социально-экономического бремени табакокурения в Российской Федерации (РФ) за 2017 г.</p><sec><title>Материлы и методы</title><p>Материлы и методы. Бремя рассчитывали на всю популяцию курильщиков РФ и сравнивали с равной по величине популяцией бросивших курить и некурящих.</p></sec><sec><title>Результаты</title><p>Результаты. В 2017 г. бремя табакокурения (включающее прямые затраты на оказание медицинской помощи и выплата по листкам временной нетрудоспособности, а также косвенные затраты - недополученный валовый внутренний продукт (ВВП) в связи с временной утратой трудоспособности) - составило 510,6 млрд руб. Разница между курильщиками и равной по величине популяцией некурящих составляет 327,6 млрд руб. Разница между курящими и равной по величине популяцией бросивших курить составила 216,1 млрд руб.</p></sec><sec><title>Заключение</title><p>Заключение. Затраты, связанные с курением, составляют значительную сумму. Любые способы помощи в отказе от табака (государственые меры по борьбе с курением, фармакологическая терапия) позволят не только увеличить качество и продолжительность жизни курильщиков, но и сэкономить внушительные суммы.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>табакокурение</kwd><kwd>фармакоэкономический анализ</kwd><kwd>социально-экономическое бремя</kwd><kwd>прямые и косвенные затраты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>smoking</kwd><kwd>pharmacoeconomic analysis</kwd><kwd>socio-economic burden</kwd><kwd>direct and indirect costs</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Forouzanfar M.H. et al. 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