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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">farmaec</journal-id><journal-title-group><journal-title xml:lang="en">FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology</journal-title><trans-title-group xml:lang="ru"><trans-title>ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2070-4909</issn><issn pub-type="epub">2070-4933</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">farmaec-25</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Methodology</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Методология фармакоэкономического анализа</subject></subj-group></article-categories><title-group><article-title>METHODOLOGICAL BASIS OF STANDARD GAMBLE METHOD USAGE IN QUALITY OF LIFE ASSESSMENT IN PHARMACOECONOMIC RESEARCHES</article-title><trans-title-group xml:lang="ru"><trans-title>МЕТОДОЛОГИЧЕСКИЕ ОСНОВЫ ИСПОЛЬЗОВАНИЯ МЕТОДА «СТАНДАРТНЫХ РИСКОВ» ПРИ ОЦЕНКЕ КАЧЕСТВА ЖИЗНИ В ФАРМАКОЭКОНОМИЧЕСКИХ ИССЛЕДОВАНИЯХ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ягудина</surname><given-names>Р. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yagudina</surname><given-names>R. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра организации лекарственного обеспечения и фармакоэкономики</p></bio><bio xml:lang="en"><p>Department of medical provision organization and pharmacoeconomics</p><p> </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куликов</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulikov</surname><given-names>A. Ju.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра организации лекарственного обеспечения и фармакоэкономики</p></bio><bio xml:lang="en"><p>Department of medical provision organization and pharmacoeconomics</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Угрехелидзе</surname><given-names>Д. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ugrekhelidze</surname><given-names>D. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра организации лекарственного обеспечения и фармакоэкономики</p></bio><bio xml:lang="en"><p>Department of medical provision organization and pharmacoeconomics</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ГБОУ ВПО «Первый МГМУ имени И.М. Сеченова» Минздрава РФ, Москва<country>Россия</country></aff><aff xml:lang="en">State Federal-Funded Educational Institution of Higher Vocational Training I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>19</day><month>03</month><year>2015</year></pub-date><volume>6</volume><issue>3</issue><fpage>3</fpage><lpage>9</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Yagudina R.I., Kulikov A.J., Ugrekhelidze D.T., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Ягудина Р.И., Куликов А.Ю., Угрехелидзе Д.Т.</copyright-holder><copyright-holder xml:lang="en">Yagudina R.I., Kulikov A.J., Ugrekhelidze D.T.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pharmacoeconomics.ru/jour/article/view/25">https://www.pharmacoeconomics.ru/jour/article/view/25</self-uri><abstract><p>Utility assessment is one of the most important stages of pharmacoeconomic analysis. Most of utility researches are conducted using standard gamble method which is considered the classic instrument of health state utilities assessment. This article presents a methodology of conducting researches using standard gamble. The problems and features of the interpretation of the results are covered, examples of research using props, as well as computer programs that calculate the values of the utility automatically are described.</p></abstract><trans-abstract xml:lang="ru"><p>Оценка полезности является одним из важнейших этапов фармакоэкономического анализа. Большая часть исследований полезности проводится с использованием метода «стандартных рисков», считающегося классическим видом оценки полезности состояний здоровья. Данная статья представляет основу методологии проведения исследования с использованием метода «стандартных рисков». Раскрыты проблемы и особенности интерпретации полученных результатов, представлены примеры исследования с использованием наглядных пособий, а также компьютерных программ, рассчитывающих значения полезности в автоматическом режиме.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фармакоэкономика</kwd><kwd>метод «стандартных рисков»</kwd><kwd>оценка предпочтений пациента</kwd><kwd>полезность</kwd><kwd>теория ожидаемой полезности</kwd><kwd>теория риска</kwd><kwd>QALY</kwd><kwd>функция полезности Неймана-Моргенштерна</kwd><kwd>компьютеризированный метод «стандартных рисков»</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pharmacoeconomics</kwd><kwd>standard gamble method</kwd><kwd>preference value assessment</kwd><kwd>utility</kwd><kwd>expected utility hypothesis</kwd><kwd>theory of risk</kwd><kwd>QALY</kwd><kwd>von Neumann-Morgenstern utility functions</kwd><kwd>computerized standard gamble method</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дж. фон Нейман, Моргенштерн О. 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