<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">farmaec</journal-id><journal-title-group><journal-title xml:lang="en">FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology</journal-title><trans-title-group xml:lang="ru"><trans-title>ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2070-4909</issn><issn pub-type="epub">2070-4933</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2070-4909.2018.11.2.038-043</article-id><article-id custom-type="elpub" pub-id-type="custom">farmaec-249</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group></article-categories><title-group><article-title>Clinical and economic efficiency of the loop ileostomy closure by various methods</article-title><trans-title-group xml:lang="ru"><trans-title>Медицинская и экономическая эффективность различных способов ликвидации петлевой илеостомы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Веселов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Veselov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Веселов Алексей Викторович – к. м.н., руководитель отдела  по организационной работе и развитию колопроктологической службы.</p><p>ул. Саляма Адиля, д. 2, Москва 123423.</p></bio><bio xml:lang="en"><p>Veselov Aleksej Viktorovich – MD, PhD, Head of Management and development of Coloproctology Care Department.</p><p>2 Salyama Adilya Str., Moscow 123423.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname> Ачкасов</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Achkasov</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ачкасов Сергей Иванович – д. м.н., профессор, руководитель отдела онкологии и хирургии ободочной кишки.</p><p>ул. Саляма Адиля, д. 2, Москва 123423.</p></bio><bio xml:lang="en"><p>Achkasov Sergej Ivanovich – MD, Professor &amp; Head, Department of Oncology and Colon Surgery.</p><p>2 Salyama Adilya Str., Moscow 123423.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сушков</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sushkov</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сушков Олег Иванович – к. м.н., старший научный сотрудник отдела онкологии и хирургии ободочной кишки.</p><p> </p></bio><bio xml:lang="en"><p>Sushkov Oleg Ivanovich – MD, PhD, Senior Researcher, Department of Oncology and Colon Surgery.</p><p>2 Salyama Adilya Str., Moscow 123423.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Москалев</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Moskalev</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москалев Алексей Игоревич – к. м.н., руководитель отдела дополнительного профессионального образования.</p><p> </p></bio><bio xml:lang="en"><p>Moskalev Aleksej Igorevich – MD, PhD, Head of the Department of Continuing Professional Education.</p><p>2 Salyama Adilya Str., Moscow 123423.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ланцов</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lantsov</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ланцов Иван Сергеевич – аспирант отдела онкологии и хирургии ободочной кишки.</p><p>ул. Саляма Адиля, д. 2, Москва 123423.</p></bio><bio xml:lang="en"><p>Lantsov Ivan Sergeevich – Post-graduate Student, Department of Oncology and Colon Surger.</p><p>2 Salyama Adilya Str., Moscow 123423.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное учреждение «Государственный научный центр колопроктологии имени А. Н. Рыжих» Министерства здравоохранения Российской Федерации .<country>Россия</country></aff><aff xml:lang="en">State Scientific Centre of Coloproctology named after A. N. Ryzhih.<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>14</day><month>08</month><year>2018</year></pub-date><volume>11</volume><issue>2</issue><fpage>38</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Veselov A.V., Achkasov S.I., Sushkov O.I., Moskalev A.I., Lantsov I.S., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Веселов А.В.,  Ачкасов С.И., Сушков О.И., Москалев А.И., Ланцов И.С.</copyright-holder><copyright-holder xml:lang="en">Veselov A.V., Achkasov S.I., Sushkov O.I., Moskalev A.I., Lantsov I.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pharmacoeconomics.ru/jour/article/view/249">https://www.pharmacoeconomics.ru/jour/article/view/249</self-uri><abstract><p>in the context of optimizing the financial mechanisms of the national healthcare system, introducing the single-channel financial principle and further developing the insurance-based medicine in Russia, a competent financial accounting becomes an important element of the entire healthcare system.</p><p>Aim – compare the economic effectiveness of various methods of closing a loop ileostomy.</p><sec><title>Materials and methods</title><p>Materials and methods. The study included 327 patients randomized into 3 groups. in group 1, the closure of an ileostomy was performed manually with the formation of an end-to-end ileo-ileoastomosis; in group 2, the anastomosis was formed in the ”side by side” manner; and in group 3, a semi-automated surgical technique was used for the anastomosis formation.</p></sec><sec><title>Results</title><p>Results. The average cost of the treatments (per patient) in groups 1 and 2 was 131,704.90 rubles. and 145,473.70 rubles, respectively, while in group 3, the cost was higher – 167,443,60 rubles (p &lt;0,001). This cost increase in Group 3 was mainly due to the cost of a disposable stapler and cassettes.</p></sec><sec><title>Conclusion</title><p>Conclusion. The formation of a manual ileoileoanastomosis of the end-to-end type was less budget-consuming in comparison with the other methods. The semi-automated procedure based on disposable parts was the most expensive method of closing a loop ileostomy.</p></sec></abstract><trans-abstract xml:lang="ru"><p>В условиях оптимизации финансирования медицинской отрасли, внедрения одноканального финансирования и системы страховой медицины в России возникает необходимость вести грамотный финансовый учет материальных затрат.</p><p>Цель – сравнить экономическую эффективность различных способов ликвидации петлевой илеостомы.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование включено 327 пациентов, которые были рандомизированы в три группы. В группе 1 закрытие илеостомы выполнено ручным способом с формированием илео-илеоанастомоза по типу «конец-в-конец», во группе 2 наложение анастомоза осуществлялось по типу «бок-в-бок», в группе 3 использовалась аппаратная методика формирования анастомоза.</p></sec><sec><title>Результаты</title><p>Результаты. Усредненные затраты лечения на одного пациента в группах 1 и 2 составили 131704,90 руб. и 145473,70 руб. соответственно, в то время как в группе 3 стоимость была выше – 167443,60 руб. (р&lt;0,001). Увеличение стоимости в группе 3 в основном было обусловлено стоимостью одноразового сшивающего аппарата и кассет.</p></sec><sec><title>Выводы</title><p>Выводы. Формирование ручного илео-илеоанастомоза по типу «конец-в-конец» было экономически более выгодным в сравнении с другими способами. Использование аппаратной методики оказалось самым дорогим методом ликвидации петлевой илеостомы за счет стоимости расходных материалов. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Закрытие двуствольной илеостомы</kwd><kwd>ликвидация превентивной илеостомы</kwd><kwd>закрытие илеостомы</kwd><kwd>илеостомия по Торнболлу</kwd><kwd>формирование илео-илеоанастомоза</kwd><kwd>ручной анастомоз</kwd><kwd>аппаратный анастомоз</kwd><kwd>стоимость закрытия илеостомы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Loop ileostomy closure</kwd><kwd>reversal ileostomy closure</kwd><kwd>ileostomy closure</kwd><kwd>manually sutured anastomosis</kwd><kwd>stapled anastomosis</kwd><kwd>ileostomy closure cost</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ulrich A. B. et al. Diverting stoma after low anterior resection: more arguments in favor. Dis. Colon Rectum. 2009; 52 (3): 412-418.</mixed-citation><mixed-citation xml:lang="en">Ulrich A. B. et al. Diverting stoma after low anterior resection: more arguments in favor.  Dis. Colon Rectum. 2009; 52 (3): 412-418.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Amin S. N. Armitage N. C., Scholefield J. H. M.A.M. Defunctioning loop ileostomy and stapled side-to-side closure has low morbidity. R. Coll. Surg. Engl. 2001; 83: 246-249.</mixed-citation><mixed-citation xml:lang="en">Amin S. N. Armitage N. C., Scholefield J. H. M.A.M. Defunctioning loop ileostomy and stapled side-to-side closure has low morbidity. R. Coll. Surg. engl. 2001; 83: 246-249.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Hirotoshi Hasegawa Simon Radley, Dion G. Morton, Michael R. B. Keighley Stapled Versus Sutured Closure of LoopIleostomyA Randomized Controlled Trial. Ann Surg. 2000; 231 (2): 202-204.</mixed-citation><mixed-citation xml:lang="en">Hirotoshi Hasegawa Simon Radley, Dion G. Morton, Michael R. B. Keighley Stapled Versus Sutured Closure of LoopIleostomyA Randomized Controlled Trial. Ann Surg. 2000; 231 (2): 202-204.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bain I. M., Patel R., Keighley M. R. Comparison of sutured and stapled closure of loop ileostomy after restorative proctocolectomy. Annals of The Royal College of Surgeons of England. 1996; 78 (6): 555-556.</mixed-citation><mixed-citation xml:lang="en">Bain I. M., Patel R., Keighley M. R. Comparison of sutured and stapled closure of loop ileostomy after restorative proctocolectomy. Annals of The Royal College of Surgeons of england. 1996; 78 (6): 555-556.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Feinberg S. M., McLeod R.S., Cohen Z. Complications of loop ileostomy. Am. J. Surg. United States. 1987; 153 (1): 102-107.</mixed-citation><mixed-citation xml:lang="en">Feinberg S. M., McLeod R.S., Cohen Z. Complications of loop ileostomy. Am. J. Surg. United States. 1987; 153 (1): 102-107.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Wong K. S. et al. Loop ileostomy closure after restorative proctocolectomy: Outcome in 1,504 patients. Dis. Colon Rectum. 2005; 48 (2): 243-250.</mixed-citation><mixed-citation xml:lang="en">Wong K. S. et al. Loop ileostomy closure after restorative proctocolectomy: Outcome in 1,504 patients. Dis. Colon Rectum. 2005; 48 (2): 243-250.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kann B. Early Stomal Complications. Clin. Colon Rectal Surg. 2008; 21( ): 023-030.</mixed-citation><mixed-citation xml:lang="en">Kann B. Early Stomal Complications. Clin. Colon Rectal Surg. 2008; 21( ): 023-030.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Harris D. et al. Complications and mortality following stoma formation. Ann. R. Coll. Surg. Engl. 2005; 87 (6): 427-431.</mixed-citation><mixed-citation xml:lang="en">Harris D. et al. Complications and mortality following stoma formation. Ann. R. Coll. Surg. engl. 2005; 87 (6): 427-431.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Robertson I. et al. Prospective analysis of stoma-related complications. Color. Dis. 2005; . 7 (3): 279-285.</mixed-citation><mixed-citation xml:lang="en">Robertson I. et al. Prospective analysis of stoma-related complications. Color. Dis. 2005; 7 (3): 279-285.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Kock N. G. Intra-abdominal “reservoir” in patients with permanent ileostomy: Preliminary observations on a procedure resulting in fecal “continence” in five ileostomy patients. Arch. Surg. 1969; 99 (2): 223-231.</mixed-citation><mixed-citation xml:lang="en">NG K. Intra-abdominal “reservoir” in patients with permanent ileostomy: Preliminary observations on a procedure resulting in fecal “continence” in five ileostomy patients. Arch. Surg. 1969; 99 (2): 223231.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Loffler T. et al. HAnd Suture Versus STApling for Closure of Loop Ileostomy (HASTA Trial): results of a multicenter randomized trial (DRKS00000040). Ann Surg. 2012; 256 (5): 826-828.</mixed-citation><mixed-citation xml:lang="en">Loffler T. et al. HAnd Suture Versus STApling for Closure of Loop Ileostomy (HASTA Trial): results of a multicenter randomized trial (DRKS00000040). Ann Surg. 2012; 256 (5): 826-828.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Luglio G. et al. Ileostomy reversal with handsewn techniques. Short-term outcomes in a teaching hospital. Int. J. Colorectal Dis. 2017; 32 (1): 113-118.</mixed-citation><mixed-citation xml:lang="en">Luglio G. et al. Ileostomy reversal with handsewn techniques. Short-term outcomes in a teaching hospital. int. J. Colorectal Dis. 2017; 32 (1): 113-118.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Сушков О. И. Результаты лапароскопических операций по поводу рака правой половины ободочной кишки: 04200602537. М. 2006; 158 с.</mixed-citation><mixed-citation xml:lang="en">Sushkov O. I. Results of laparoscopic operations for cancer of the right colon: 04200602537 [Rezul’taty laparoskopicheskih operacij po povodu raka pravoj poloviny obodochnoj kishki: 04200602537 (in Russian). Moscow. 2006; 158 s.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Воробьев Г. И., Шелыгин Ю. А., Фролов С. Ф., Сушков О. И. Оценка экономической эффективности применения лапароскопических технологий при выполнении правосторонней гемиколэктомии по поводу рака. Эндоскопическая хирургия. 2007;. 13 (1): 26.</mixed-citation><mixed-citation xml:lang="en">Vorob’ev G.I., Shelygin Yu.A., Frolov S. F., Sushkov O. I. ehndos kopicheskaya hirurgiya (in Russian). 2007; 13 (1): 26.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Horisberger K., Beldi G., Candinas D. Loop ileostomy closure: comparison of cost effectiveness between suture and stapler.World J Surg. 2010; 34 (12): 2867-2871.</mixed-citation><mixed-citation xml:lang="en">Horisberger K., Beldi G., Candinas D. Loop ileostomy closure: comparison of cost effectiveness between suture and stapler. World J Surg. 2010; 34 (12): 2867-2871.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Tracy L. Hull Ingrid Kobe, Victor W. Fazio Comparison of Handsewn with Stapled Loop Ileostomy Closures. Dis. Colon Rectum. 1995; 39 (10):1086-9.</mixed-citation><mixed-citation xml:lang="en">Tracy L. Hull Ingrid Kobe, Victor W. Fazio Comparison of  Handsewn with Stapled Loop Ileostomy Closures. Dis. Colon Rectum. 1995; 39 (10):1086-9.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Shelygin Y. A., Chernyshov S. V., Rybakov E. G. Stapled ileostomy closure results in reduction of postoperative morbidity. Tech Coloproctol. 2010; 14 (1): 19-23.</mixed-citation><mixed-citation xml:lang="en">Shelygin Y. A., Chernyshov S. V., Rybakov E. G. Stapled ileostomy closure results in reduction of postoperative morbidity. Tech Coloproctol. 2010; 14 (1): 19-23.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Huser N. et al. Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery. Ann Surg. 2008; 248 (1): 52-60.</mixed-citation><mixed-citation xml:lang="en">Huser N. et al. Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery. Ann Surg. 2008; 248 (1): 52-60.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Man V. C. et al. Morbidities after closure of ileostomy: analysis of risk factors. Int J Color. Dis. 2016; 31 (1): 51-57.</mixed-citation><mixed-citation xml:lang="en">Man V. C. et al. Morbidities after closure of ileostomy: analysis of risk factors. int J Color. Dis. 2016; 31 (1): 51-57.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Gaetano Luglio, Stefan D. Holubar, Robert R. Cima, Heidi Nelson. Loop Ileostomy Reversal After Colonand Rectal Surgery. Arch Surg. 2011; 146 (10): 1191-6.</mixed-citation><mixed-citation xml:lang="en">Gaetano Luglio, Stefan D. Holubar, Robert R. Cima, Heidi Nelson. Loop Ileostomy Reversal After Colonand Rectal Surgery. Arch Surg. 2011; 146 (10): 1191-6.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Leung T. T. et al. Comparison of stapled versus handsewn loop ileostomy closure: a meta-analysis. J Gastrointest Surg. 2008; 12 (5): 939-944.</mixed-citation><mixed-citation xml:lang="en">Leung T. T. et al. Comparison of stapled versus handsewn loop ileostomy closure: a meta-analysis. J Gastrointest Surg. 2008; 12 (5): 939-944.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Poskus E. et al. Complications after Loop Ileostomy Closure: A Retrospective Analysis of 132 Patients. Viszeralmedizin. 2014; 30 (4): 276-280.</mixed-citation><mixed-citation xml:lang="en">Poskus E. et al. Complications after Loop Ileostomy Closure: A Retrospective Analysis of 132 Patients. Viszeralmedizin. 2014; 30 (4): 276-280.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Mennigen R. et al. Morbidity of loop ileostomy closure after restorative proctocolectomy for ulcerative colitis and familial adenomatous polyposis: a systematic review. J Gastrointest Surg. 2014; 18 (12): 2192-2200.</mixed-citation><mixed-citation xml:lang="en">Mennigen R. et al. Morbidity of loop ileostomy closure after restorative proctocolectomy for ulcerative colitis and familial adenomatous polyposis: a systematic review. J Gastrointest Surg. 2014; 18 (12): 2192-2200.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Markides G. A. et al. Meta-analysis of handsewn versus stapled reversal of loop ileostomy. ANZ J Surg. 2015; 85 (4): 217-224.</mixed-citation><mixed-citation xml:lang="en">Markides G. A. et al. Meta-analysis of handsewn versus stapled reversal of loop ileostomy. AnZ J Surg. 2015; 85 (4): 217-224.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Mansfield S. D. et al. Complications of loop ileostomy closure: a retrospective cohort analysis of 123 patients. World J Surg. 2008; 32 (9): 2101-2106.</mixed-citation><mixed-citation xml:lang="en">Mansfield S. D. et al. Complications of loop ileostomy closure: a retrospective cohort analysis of 123 patients. World J Surg. 2008; 32 (9): 2101-2106.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Williams L. A. et al. The outcome of loop ileostomy closure: a prospective study. Color. Dis. 2008; 10 (5): 460-464.</mixed-citation><mixed-citation xml:lang="en">Williams L. A. et al. The outcome of loop ileostomy closure: a prospective study. Color. Dis. 2008; 10 (5): 460-464.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Шелыгин Ю. А. et al. Роль антибиотикопрофилактики при ликвидации превентивных кишечных стом. Колопроктология. 2016; 2 (56): 25-31.</mixed-citation><mixed-citation xml:lang="en">Shelygin Yu.A. et al. koloproktologiya (in Russian). 2016; 2 (56): 25-31.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Шелыгин Ю.А., Веселов А.В., Сербина А.А. Основные направления организации специализированной колопроктологической помощи. Колопроктология. 2017; 1 (59): 76-81.</mixed-citation><mixed-citation xml:lang="en">Shelygin Yu.A. et al. koloproktologiya (in Russian). 2017; 1 (59): 76-81.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
